CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024
Operating activities
Net income (loss)	$ (559,599)	$ 369,005
Adjustments to reconcile net income (loss) to net cash provided by operating activities:
Acquired in-process research and development	947,862	10,000
Intangible asset amortization	484,919	468,410
Share-based compensation	220,279	177,855
Acquisition accounting inventory fair value step-up adjustment	107,344	97,220
Depreciation	32,209	23,240
Non-cash interest expense	27,213	18,877
Provision for losses on accounts receivable and inventory	14,994	15,866
Deferred tax benefit	(381,662)	(205,972)
Other non-cash transactions	8,058	19,615
Changes in assets and liabilities:
Accounts receivable	(40,466)	(21,979)
Inventories	(93,761)	(26,877)
Prepaid expenses and other current assets	1,538	708
Operating lease assets	15,618	10,697
Other non-current assets	18,022	(9,544)
Accounts payable	68,823	(16,938)
Accrued liabilities	50,926	56,428
Income taxes payable	72,008	20,098
Operating lease liabilities, less current portion	(6,362)	(9,701)
Other non-current liabilities	5,292	320
Net cash provided by operating activities	993,255	997,328
Investing activities
Acquisition of investments	(1,320,175)	(835,125)
Asset acquisition, net of cash acquired	(858,053)	0
Acquisition of intangible assets	(55,000)	0
Acquired in-process research and development	(42,500)	(10,000)
Purchases of property, plant and equipment	(42,023)	(24,783)
Proceeds from maturity of investments	1,180,000	555,000
Net cash used in investing activities	(1,137,751)	(314,908)
Financing activities
Repayments of long-term debt	(773,250)	(23,250)
Share repurchases	(125,023)	(311,429)
Payment of employee withholding taxes related to share-based awards	(73,224)	(53,748)
Proceeds from employee equity incentive and purchase plans	22,677	11,451
Repayment of 2024 Notes	0	(575,000)
Net proceeds from issuance of 2030 Notes	0	980,767
Net cash provided by (used in) financing activities	(948,820)	28,791
Effect of exchange rates on cash and cash equivalents	6,522	614
Net increase (decrease) in cash and cash equivalents	(1,086,794)	711,825
Cash and cash equivalents, at beginning of period	2,412,864	1,506,310
Cash and cash equivalents, at end of period	$ 1,326,070	$ 2,218,135