Revenues - Schedule of Disaggregation of Revenue (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Disaggregation of Revenue [Line Items]
Total revenues	$ 1,126,107	$ 1,054,969	$ 3,069,660	$ 2,980,777
United States
Disaggregation of Revenue [Line Items]
Total revenues	1,020,476	953,669	2,755,273	2,686,486
Europe
Disaggregation of Revenue [Line Items]
Total revenues	86,405	77,318	252,206	230,821
All other
Disaggregation of Revenue [Line Items]
Total revenues	19,226	23,982	62,181	63,470
Product sales, net
Disaggregation of Revenue [Line Items]
Total revenues	1,064,412	989,707	2,889,401	2,795,953
Total Neuroscience
Disaggregation of Revenue [Line Items]
Total revenues	774,433	702,724	2,086,637	1,967,844
Xywav
Disaggregation of Revenue [Line Items]
Total revenues	431,410	388,466	1,191,535	1,072,238
Xyrem
Disaggregation of Revenue [Line Items]
Total revenues	35,663	58,114	108,253	184,526
Epidiolex/Epidyolex
Disaggregation of Revenue [Line Items]
Total revenues	302,608	251,558	772,075	697,376
Sativex
Disaggregation of Revenue [Line Items]
Total revenues	4,752	4,586	14,774	13,704
Total Oncology
Disaggregation of Revenue [Line Items]
Total revenues	287,836	284,754	791,901	819,612
Rylaze/Enrylaze
Disaggregation of Revenue [Line Items]
Total revenues	99,868	98,780	294,760	309,359
Zepzelca
Disaggregation of Revenue [Line Items]
Total revenues	79,295	85,843	216,869	241,990
Defitelio/defibrotide
Disaggregation of Revenue [Line Items]
Total revenues	51,752	65,818	140,520	158,915
Vyxeos
Disaggregation of Revenue [Line Items]
Total revenues	37,583	34,313	111,978	109,348
Ziihera
Disaggregation of Revenue [Line Items]
Total revenues	8,306	0	16,272	0
Modeyso
Disaggregation of Revenue [Line Items]
Total revenues	11,032	0	11,502	0
Other
Disaggregation of Revenue [Line Items]
Total revenues	2,143	2,229	10,863	8,497
High-sodium oxybate AG royalty revenue
Disaggregation of Revenue [Line Items]
Total revenues	52,945	58,157	156,029	162,268
Other royalty and contract revenues
Disaggregation of Revenue [Line Items]
Total revenues	$ 8,750	$ 7,105	$ 24,230	$ 22,556