CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024
Operating activities
Net income (loss)	$ (811,011)	$ 153,950
Adjustments to reconcile net income (loss) to net cash provided by operating activities:
Acquired in-process research and development	905,362	10,000
Intangible asset amortization	316,551	310,953
Share-based compensation	132,154	118,095
Acquisition accounting inventory fair value step-up adjustment	66,989	62,186
Depreciation	22,331	15,465
Non-cash interest expense	21,914	11,200
Provision for losses on accounts receivable and inventory	6,771	13,186
Deferred tax benefit	(110,252)	(141,568)
Other non-cash transactions	7,042	15,520
Changes in assets and liabilities:
Accounts receivable	10,530	277
Inventories	(61,852)	(17,591)
Prepaid expenses and other current assets	8,212	34,872
Operating lease assets	12,440	7,199
Other non-current assets	(802)	(5,699)
Accounts payable	6,465	(4,148)
Accrued liabilities	(75,351)	5,404
Income taxes payable	59,270	18,030
Operating lease liabilities, less current portion	(2,887)	(6,909)
Other non-current liabilities	4,763	(1,841)
Net cash provided by operating activities	518,639	598,581
Investing activities
Asset acquisition, net of cash acquired	(858,053)	0
Acquisition of investments	(680,050)	(705,000)
Purchases of property, plant and equipment	(26,848)	(13,995)
Acquisition of intangible assets	(25,000)	0
Proceeds from maturity of investments	780,000	200,000
Acquired in-process research and development	0	(10,000)
Net cash used in investing activities	(809,951)	(528,995)
Financing activities
Repayments of long-term debt	(765,500)	(15,500)
Share repurchases	(125,023)	(161,428)
Payment of employee withholding taxes related to share-based awards	(69,412)	(52,143)
Proceeds from employee equity incentive and purchase plans	21,944	11,434
Net cash used in financing activities	(937,991)	(217,637)
Effect of exchange rates on cash and cash equivalents	6,319	(2,457)
Net decrease in cash and cash equivalents	(1,222,984)	(150,508)
Cash and cash equivalents, at beginning of period	2,412,864	1,506,310
Cash and cash equivalents, at end of period	$ 1,189,880	$ 1,355,802