Revenues - Schedule of Disaggregation of Revenue (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
Disaggregation of Revenue [Line Items]
Total revenues	$ 1,045,712	$ 1,023,825	$ 1,943,553	$ 1,925,808
United States
Disaggregation of Revenue [Line Items]
Total revenues	936,283	924,592	1,734,797	1,732,806
Europe
Disaggregation of Revenue [Line Items]
Total revenues	82,763	82,159	165,801	153,514
All other
Disaggregation of Revenue [Line Items]
Total revenues	26,666	17,074	42,955	39,488
Product sales, net
Disaggregation of Revenue [Line Items]
Total revenues	985,571	964,144	1,824,989	1,806,246
Total Neuroscience
Disaggregation of Revenue [Line Items]
Total revenues	707,015	684,137	1,312,204	1,265,120
Xywav
Disaggregation of Revenue [Line Items]
Total revenues	415,321	368,472	760,125	683,772
Xyrem
Disaggregation of Revenue [Line Items]
Total revenues	35,349	62,180	72,590	126,412
Epidiolex/Epidyolex
Disaggregation of Revenue [Line Items]
Total revenues	251,730	247,102	469,467	445,818
Sativex
Disaggregation of Revenue [Line Items]
Total revenues	4,615	6,383	10,022	9,118
Total Oncology
Disaggregation of Revenue [Line Items]
Total revenues	274,148	277,309	503,595	534,858
Rylaze/Enrylaze
Disaggregation of Revenue [Line Items]
Total revenues	100,659	107,829	194,892	210,579
Zepzelca
Disaggregation of Revenue [Line Items]
Total revenues	74,541	81,047	137,574	156,147
Defitelio/defibrotide
Disaggregation of Revenue [Line Items]
Total revenues	48,106	45,421	88,768	93,097
Vyxeos
Disaggregation of Revenue [Line Items]
Total revenues	44,851	43,012	74,395	75,035
Ziihera
Disaggregation of Revenue [Line Items]
Total revenues	5,991	0	7,966	0
Other
Disaggregation of Revenue [Line Items]
Total revenues	4,408	2,698	9,190	6,268
High-sodium oxybate AG royalty revenue
Disaggregation of Revenue [Line Items]
Total revenues	54,138	54,164	103,084	104,111
Other royalty and contract revenues
Disaggregation of Revenue [Line Items]
Total revenues	$ 6,003	$ 5,517	$ 15,480	$ 15,451