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Certain Balance Sheet Items - Accrued Liabilities (Details) - USD ($)
$ in Thousands
Jun. 30, 2020
Dec. 31, 2019
Certain Balance Sheet Items [Abstract]    
Rebates and other sales deductions $ 122,204 $ 96,860
Employee compensation and benefits 51,289 80,531
Current portion of operating lease liabilities 12,763 12,728
Inventory-related accruals 12,364 7,816
Sales returns reserve 8,030 3,462
Derivative instrument liabilities 7,064 1,037
Consulting and professional services 6,221 7,665
Accrued interest 6,110 7,540
Royalties 6,031 6,931
Selling and marketing accruals 3,420 10,946
Accrued collaboration expenses 3,161 2,494
Clinical trial accruals 2,965 3,141
Accrued construction-in-progress 442 3,015
Other 24,854 25,520
Total accrued liabilities $ 266,918 $ 269,686