Certain Balance Sheet Items - (Tables)

6 Months Ended

Jun. 30, 2020

Certain Balance Sheet Items [Abstract]

Schedule of Property and Equipment

Property, plant and equipment consisted of the following (in thousands):

	June 30, 2020			December 31, 2019
Leasehold improvements	$	53,348		$	52,294
Land and buildings	47,112			47,053
Manufacturing equipment and machinery	30,840			28,860
Computer software	22,758			25,680
Computer equipment	17,747			16,577
Furniture and fixtures	11,330			11,152
Construction-in-progress	3,393			5,147
Subtotal	186,528			186,763
Less accumulated depreciation and amortization	(58,269		)	(55,257		)
Property, plant and equipment, net	$	128,259		$	131,506

Schedule of Accrued Liabilities

Accrued liabilities consisted of the following (in thousands):

	June 30, 2020		December 31, 2019
Rebates and other sales deductions	$	122,204	$	96,860
Employee compensation and benefits	51,289		80,531
Current portion of operating lease liabilities	12,763		12,728
Inventory-related accruals	12,364		7,816
Sales returns reserve	8,030		3,462
Derivative instrument liabilities	7,064		1,037
Consulting and professional services	6,221		7,665
Accrued interest	6,110		7,540
Royalties	6,031		6,931
Selling and marketing accruals	3,420		10,946
Accrued collaboration expenses	3,161		2,494
Clinical trial accruals	2,965		3,141
Accrued construction-in-progress	442		3,015
Other	24,854		25,520
Total accrued liabilities	$	266,918	$	269,686