Certain Balance Sheet Items - (Tables)

3 Months Ended

Mar. 31, 2020

Certain Balance Sheet Items [Abstract]

Property and Equipment

Property, plant and equipment consisted of the following (in thousands):

	March 31, 2020			December 31, 2019
Leasehold improvements	$	52,275		$	52,294
Land and buildings	47,040			47,053
Manufacturing equipment and machinery	29,961			28,860
Computer software	23,044			25,680
Computer equipment	16,932			16,577
Furniture and fixtures	11,281			11,152
Construction-in-progress	4,472			5,147
Subtotal	185,005			186,763
Less accumulated depreciation and amortization	(55,443		)	(55,257		)
Property, plant and equipment, net	$	129,562		$	131,506

Accrued Liabilities

Accrued liabilities consisted of the following (in thousands):

	March 31, 2020		December 31, 2019
Rebates and other sales deductions	$	121,369	$	96,860
Employee compensation and benefits	52,080		80,290
Current portion of operating lease liabilities	12,357		12,728
Derivative instrument liabilities	8,663		1,037
Selling and marketing accruals	8,443		11,299
Inventory-related accruals	7,706		7,816
Sales returns reserve	4,519		3,462
Accrued collaboration expenses	3,865		2,494
Professional fees	3,495		4,718
Royalties	2,654		6,931
Accrued interest	2,520		7,386
Clinical trial accruals	2,473		2,551
Accrued construction-in-progress	256		1,564
Other	30,641		28,737
Total accrued liabilities	$	261,041	$	267,873