Condensed Consolidated Statements Of Income - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Revenues:
Total revenues	$ 534,133	$ 500,479	$ 1,042,319	$ 945,092
Operating expenses:
Cost of product sales (excluding amortization of intangible assets)	27,676	34,714	61,182	68,633
Selling, general and administrative	176,014	158,579	343,961	365,792
Research and development	62,384	56,132	122,489	118,799
Intangible asset amortization	61,576	54,959	118,461	107,966
Impairment charges	0	42,896	0	42,896
Acquired in-process research and development	2,200	0	58,200	0
Total operating expenses	329,850	347,280	704,293	704,086
Income from operations	204,283	153,199	338,026	241,006
Interest expense, net	(18,234)	(19,646)	(36,156)	(40,251)
Foreign exchange loss	(1,933)	(2,697)	(2,544)	(4,425)
Loss on extinguishment and modification of debt	0	(1,425)	0	(1,425)
Income before income tax provision (benefit) and equity in loss of investees	184,116	129,431	299,326	194,905
Income tax provision (benefit)	(78,650)	36,524	(49,534)	55,670
Equity in loss of investees	868	586	1,761	923
Net income	$ 261,898	$ 92,321	$ 347,099	$ 138,312
Net income per ordinary share:
Basic (in dollars per share)	$ 4.62	$ 1.53	$ 6.09	$ 2.30
Diluted (in dollars per share)	$ 4.56	$ 1.50	$ 6.01	$ 2.26
Weighted-average ordinary shares used in per share calculations - basic (in shares)	56,707	60,177	56,955	60,053
Weighted-average ordinary shares used in per share calculations - diluted (in shares)	57,427	61,438	57,753	61,309
Product sales, net
Revenues:
Total revenues	$ 523,423	$ 496,095	$ 1,026,754	$ 936,942
Royalties and contract revenues
Revenues:
Total revenues	$ 10,710	$ 4,384	$ 15,565	$ 8,150