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Property, Plant and Equipment
12 Months Ended
Dec. 31, 2018
Property, Plant and Equipment [Abstract]  
Property and Equipment
Property, Plant and Equipment
Property, plant and equipment consisted of the following (in thousands): 
 
December 31,
 
2018
 
2017
Build-to-suit facility
$
52,067

 
$
51,721

Construction-in-progress
51,243

 
21,738

Land and buildings
46,650

 
46,729

Leasehold improvements
33,273

 
28,779

Manufacturing equipment and machinery
25,837

 
23,586

Computer software
19,062

 
19,969

Computer equipment
13,679

 
12,814

Furniture and fixtures
8,155

 
5,947

Subtotal
249,966

 
211,283

Less accumulated depreciation and amortization
(49,608
)
 
(41,203
)
Property, plant and equipment, net
$
200,358

 
$
170,080


Depreciation and amortization expense (including amortization expense related to a facility lease) on property, plant and equipment amounted to $15.2 million, $13.1 million and $11.8 million for the years ended December 31, 2018, 2017 and 2016, respectively.