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Revenues (Tables)
6 Months Ended
Jun. 30, 2018
Revenue from Contract with Customer [Abstract]  
Summary of disaggregation of revenue
The following table presents a summary of total revenues (in thousands): 
 
Three Months Ended
June 30,
 
Six Months Ended
June 30,
 
2018
 
2017
 
2018
 
2017
Xyrem
$
356,008

 
$
298,026

 
$
672,785

 
$
570,352

Erwinaze/Erwinase
58,713

 
49,024

 
109,340

 
100,412

Defitelio/defibrotide
40,498

 
30,238

 
75,559

 
66,138

Vyxeos
27,951

 

 
54,179

 

Prialt
8,921

 
5,656

 
15,047

 
13,373

Other
4,004

 
6,711

 
10,032

 
13,058

Product sales, net
496,095

 
389,655

 
936,942

 
763,333

Royalties and contract revenues
4,384

 
4,731

 
8,150

 
7,106

Total revenues
$
500,479

 
$
394,386

 
$
945,092

 
$
770,439

The following table presents a summary of total revenues attributed to geographic sources (in thousands): 
 
Three Months Ended
June 30,
 
Six Months Ended
June 30,
 
2018
 
2017
 
2018
 
2017
United States
$
455,359

 
$
356,687

 
$
861,046

 
$
695,870

Europe
35,018

 
27,378

 
63,349

 
58,730

All other
10,102

 
10,321

 
20,697

 
15,839

Total revenues
$
500,479

 
$
394,386

 
$
945,092

 
$
770,439

Summary of Revenues from Customers Representing More Than 10% of Total Revenues
The following table presents a summary of the percentage of total revenues from customers that represented more than 10% of our total revenues: 
 
Three Months Ended
June 30,
 
Six Months Ended
June 30,
 
2018
 
2017
 
2018
 
2017
Express Scripts
71
%
 
75
%
 
71
%
 
74
%
McKesson
20
%
 
14
%
 
20
%
 
15
%
Summary of a reconciliation in contract liabilities from contracts with customer
The following table presents a reconciliation of our beginning and ending balances in contract liabilities from contracts with customers for the six months ended June 30, 2018 (in thousands): 
 
Contract Liabilities
Balance as of December 31, 2017
$
24,733

Effect of adoption of ASU 2014-09
(2,240
)
Amount recognized within royalties and contract revenues
(3,749
)
Balance as of June 30, 2018
$
18,744