Condensed Consolidated Statements Of Income - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017
Revenues:
Total revenues	$ 500,479	$ 394,386	$ 945,092	$ 770,439
Operating expenses:
Cost of product sales (excluding amortization of intangible assets)	34,714	28,672	68,633	53,737
Selling, general and administrative	158,579	132,328	365,792	276,583
Research and development	56,132	40,157	118,799	85,085
Intangible asset amortization	54,959	26,186	107,966	51,851
Impairment charges	42,896	0	42,896	0
Acquired in-process research and development	0	2,000	0	2,000
Total operating expenses	347,280	229,343	704,086	469,256
Income from operations	153,199	165,043	241,006	301,183
Interest expense, net	(19,646)	(18,294)	(40,251)	(37,138)
Foreign exchange loss	(2,697)	(5,427)	(4,425)	(6,891)
Loss on extinguishment and modification of debt	(1,425)	0	(1,425)	0
Income before income tax provision and equity in loss of investees	129,431	141,322	194,905	257,154
Income tax provision	36,524	35,515	55,670	64,675
Equity in loss of investees	586	203	923	364
Net income	$ 92,321	$ 105,604	$ 138,312	$ 192,115
Net income per ordinary share:
Basic (in dollars per share)	$ 1.53	$ 1.76	$ 2.30	$ 3.20
Diluted (in dollars per share)	$ 1.50	$ 1.72	$ 2.26	$ 3.13
Weighted-average ordinary shares used in per share calculations - basic (in shares)	60,177	60,100	60,053	59,991
Weighted-average ordinary shares used in per share calculations - diluted (in shares)	61,438	61,463	61,309	61,321
Product sales, net
Revenues:
Total revenues	$ 496,095	$ 389,655	$ 936,942	$ 763,333
Royalties and contract revenues
Revenues:
Total revenues	$ 4,384	$ 4,731	$ 8,150	$ 7,106