Commitments and Contingencies - Additional Information (Details) $ in Thousands			1 Months Ended				3 Months Ended	11 Months Ended	36 Months Ended
	Nov. 22, 2010	Oct. 18, 2010 patent	Apr. 30, 2016 litigation_case claim_under_petition	Mar. 31, 2016 USD ($) claim_under_petition	Jan. 31, 2015 patent	Apr. 30, 2014	Mar. 31, 2016 USD ($) product	Jan. 27, 2016 lawsuit patent	Dec. 31, 2012 patent	Dec. 31, 2015 USD ($)
Commitments and Contingencies Disclosure [Line Items]
Construction-in-progress				$ 66,185			$ 66,185			$ 63,008
Other non-current liabilities				79,207			79,207			$ 69,253
Noncancelable purchase commitments, due within one year				$ 53,400			$ 53,400
Radiopharmaceutical Products [Member]
Commitments and Contingencies Disclosure [Line Items]
Number of radiopharmaceutical products | product							2
Pending Litigation [Member] | Xyrem [Member]
Commitments and Contingencies Disclosure [Line Items]
Number of patents named in CBM petitions | patent					6
Number of petition claims PTAB denied | claim_under_petition				25
Number of petition claims accepted | claim_under_petition				3
Pending Litigation [Member] | Xyrem ANDA Matters [Member]
Commitments and Contingencies Disclosure [Line Items]
Number of patents allegedly infringed upon | patent		5						5	10
Court ordered stay period	30 months					30 months
Number of claims filed | lawsuit								3
Palo Alto [Member] | Building [Member]
Commitments and Contingencies Disclosure [Line Items]
Rent expense							$ 500
Palo Alto [Member] | Building [Member] | Property and Equipment, Net [Member]
Commitments and Contingencies Disclosure [Line Items]
Construction-in-progress				$ 5,100			5,100
Palo Alto [Member] | Building [Member] | Other Non-Current Liabilities [Member]
Commitments and Contingencies Disclosure [Line Items]
Other non-current liabilities				$ 5,100			$ 5,100
Subsequent Event [Member] | Pending Litigation [Member] | Xyrem [Member]
Commitments and Contingencies Disclosure [Line Items]
Number of petition claims PTAB denied | claim_under_petition			18
Number of petition claims accepted | claim_under_petition			16
Subsequent Event [Member] | Pending Litigation [Member] | Xyrem ANDA Matters [Member]
Commitments and Contingencies Disclosure [Line Items]
Number of patent litigation cases consolidated | litigation_case			2