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Income Taxes - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
Income Taxes [Line Items]        
Income tax provision $ 29,945 $ 24,221 $ 92,651 $ 60,598
Effective income tax rate, percentage 25.40%   27.30%  
Acquired in-process research and development $ 0 $ 75,000 $ 0 $ 202,000
Non-Taxable Jurisdiction [Member]        
Income Taxes [Line Items]        
Modified effective income tax rate, percentage   19.40%   25.40%
Ireland [Member]        
Income Taxes [Line Items]        
Effective statutory income tax rate, percentage 12.50%   12.50%