Segment and Other Information - Summary of Total Revenues (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2015	Sep. 30, 2014	Sep. 30, 2015	Sep. 30, 2014
Revenue from External Customer [Line Items]
Product sales, net	$ 338,754	$ 304,407	$ 977,895	$ 838,493
Royalties and contract revenues	2,118	2,177	6,027	6,240
Total revenues	340,872	306,584	983,922	844,733
Xyrem [Member]
Revenue from External Customer [Line Items]
Product sales, net	242,899	204,337	703,435	556,081
Erwinaze And Erwinase [Member]
Revenue from External Customer [Line Items]
Product sales, net	56,317	52,121	152,821	146,910
Defitelio [Member]
Revenue from External Customer [Line Items]
Product sales, net	19,639	18,892	52,259	51,345
Prialt [Member]
Revenue from External Customer [Line Items]
Product sales, net	6,042	6,282	19,944	16,422
Psychiatry [Member]
Revenue from External Customer [Line Items]
Product sales, net	9,910	10,833	28,375	32,431
Other [Member]
Revenue from External Customer [Line Items]
Product sales, net	$ 3,947	$ 11,942	$ 21,061	$ 35,304