Certain Balance Sheet Items - Accrued Liabilities (Details) - USD ($) $ in Thousands	Sep. 30, 2015	Dec. 31, 2014
Certain Balance Sheet Items [Abstract]
Rebates and other sales deductions	$ 63,676	$ 51,899
Employee compensation and benefits	33,893	46,143
Accrued milestone payment	25,000	0
Sales returns reserve	7,757	14,039
Royalties	5,340	7,964
Professional fees	3,808	3,295
Accrued interest	1,927	10,327
Accrued construction-in-progress	1,690	4,931
Other	23,284	25,493
Total accrued liabilities	$ 166,375	$ 164,091