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Goodwill and Intangible Assets - Additional Information (Detail) (USD $)
In Thousands, unless otherwise specified
9 Months Ended
Sep. 30, 2014
Goodwill [Roll Forward]  
Goodwill, beginning of period $ 450,456
Goodwill arising from the Gentium Acquisition 308,642
Foreign exchange (34,710)
Goodwill, end of period $ 724,388