Share-Based Compensation Expense (Detail) (Share Options And Restricted Stock Units [Member], USD $) In Thousands, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2013	Sep. 30, 2012	Sep. 30, 2013	Sep. 30, 2012
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Share-based compensation expense	$ 11,876	$ 6,355	$ 32,139	$ 14,684
Tax benefit from share-based compensation expense	(3,502)	0	(9,850)	0
Total share-based compensation expense, net of tax	8,374	6,355	22,289	14,684
Selling, general and administrative [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Share-based compensation expense	9,354	5,330	25,898	11,967
Research and development [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Share-based compensation expense	1,931	681	4,453	1,718
Cost of product sales [Member]
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Share-based compensation expense	$ 591	$ 344	$ 1,788	$ 999