X0203 3 2011-07-01 0 0000882796 BIOCRYST PHARMACEUTICALS INC BCRX 0001230708 STAAB THOMAS R II 4505 EMPEROR BLVD. SUITE 200 DURHAM NC 27703 1 Senior Vice President and CFO Common Stock 25000 D Stock Option (Right to Buy) 3.78 2012-07-01 2021-07-01 Common Stock 200000 D Restricted stock award. Will vest on the first anniversary of the date of grant, subject to continued employment on such vesting date. Options become exercisable at a rate of 25% on each of the first, second, third and fourth anniversaries of the date of grant. /s/ Alane Barnes, by power of attorney 2011-07-08