X0306 4 2018-04-03 0 0001200375 CODEXIS INC CDXS 0001229447 Smith David V C/O CODEXIS, INC. 200 PENOBSCOT DRIVE REDWOOD CITY CA 94063 1 0 0 0 Common Stock 2018-04-03 4 S 0 6000 10.3688 D 56679 I See footnote The sales reported in this Form 4 were effected pursuant to the Reporting Person's Rule 10b5-1 trading plan. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.125 to $10.60, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote. Shares held by The Smith Family Trust. /s/ Gordon Sangster, Attorney-in-Fact for David V. Smith 2018-04-05