X0306 4 2022-01-28 0001228627 Ocuphire Pharma, Inc. OCUP 0001830354 Hoffmann Bernhard C/O OCUPHIRE PHARMA, INC. 37000 GRAND RIVER AVE, SUITE 120 FARMINGTON HILLS MI 48335 true VP of Corp. Dev. & Ops & Sec. Employee Stock Option (right to buy) 2.9 2022-01-28 4 A 0 42500 0 A 2032-01-27 Common Stock 42500 42500 D The option will vest with respect to 10,625 shares on January 28, 2023, and then with respect to 885 shares on the last day of each month from February 2023 through December 2025 and with respect to 900 shares at the end of January 2026. /s/ Jeffrey Kuras, by Power of Attorney 2022-02-01