X0306 4 2022-01-28 0001228627 Ocuphire Pharma, Inc. OCUP 0001832343 Zaremba Rabourn Amy C/O OCUPHIRE PHARMA, INC. 37000 GRAND RIVER AVE, SUITE 120 FARMINGTON HILLS MI 48335 true VP of Finance Employee Stock Option (right to buy) 2.9 2022-01-28 4 A 0 50000 0 A 2032-01-27 Common Stock 50000 50000 D The option will vest with respect to 12,500 shares on January 28, 2023, and then with respect to 1,041 shares on the last day of each month from February 2023 through December 2025 and with respect to 1,065 shares at the end of January 2026. /s/ Jeffrey Kuras, by Power of Attorney 2022-02-01