Document and Entity Information. Document And Entity Information [Abstract] Statement [Table] Statement [Line Items] Document Type Document Period End Date Entity Registrant Name Entity Filer Category Entity Small Business Entity Emerging Growth Company Amendment Flag Entity Central Index Key Balance Sheet [Abstract] Assets [Abstract] Current Assets: Cash and Cash Equivalents, at Carrying Value Cash and Cash Equivalents - end of period Cash and Cash Equivalents - beginning of period Cash and cash equivalents Available-for-sale Securities, Current Marketable securities Prepaid Expense and Other Assets, Current Total prepaid expenses and other current assets Prepaid expenses and other current assets Assets, Current Total Current Assets Security Deposit Security Deposits Operating Lease, Right-of-Use Asset Operating Lease Right-of-Use Assets Right-of-Use Assets Property, Plant and Equipment, Net Equipment, Net Net carrying amount Assets Total Assets LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities [Abstract] Current Liabilities: Accounts Payable and Accrued Liabilities, Current Accounts payable and accrued expenses Contract with Customer, Liability, Current Deferred revenue Operating Lease, Liability, Current Less: current maturities of lease obligations Operating lease liabilities, current Current Liabilities, Current Total Current Liabilities Operating Lease, Liability, Noncurrent Long-term lease obligations Operating Lease Liabilities, non-current Long Term Fair values as of the balance sheet date of all liabilities resulting from warrants that meet the criteria of being accounted for as liability instruments due to a provision in the warrant agreement for net cash settlement in the event that there is a fundamental transaction (contractually defined as a merger, sale of substantially all assets, tender offer, or share exchange). Warrant Liabilities Warrant Liabilities Deferred Rent Credit, Noncurrent Other Liabilities Liabilities Total Liabilities Commitments and Contingencies (note 18) Commitments and Contingencies Statement of Stockholders' Equity (Deficit) and Comprehensive Loss Period from March 19, 2001 (Inception) to December 31, 2011 Stockholders' Equity: Preferred Stock, Value, Issued Preferred stock Common Stock, Value, Issued Common stock Additional Paid in Capital, Common Stock Additional paid-in capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive income (loss) Retained Earnings (Accumulated Deficit) Accumulated deficit Accumulated deficit Stockholders' Equity Attributable to Parent Balance Balance Total Stockholders' Equity Liabilities and Stockholders' Equity (abstract) Total Liabilities and Stockholders' Equity Preferred Stock, Par Value Preferred Stock, Shares Authorized Preferred Stock, Shares Issued Preferred Stock, Shares Outstanding Common Stock, Par Value Common Stock, Shares Authorized Common Stock, Shares, Issued Common Stock, Shares, Outstanding Balance, shares Balance, shares Statement Of Operations [Abstract] Revenues Revenues: Expenses: General and Administrative Expense General and administrative Research and Development Expense Research and development Operating Expenses Total Expenses Operating Income (Loss) Loss from Operations Other (Income) Expense Other Income Investment Income, Interest Interest income Other Nonoperating Income Other income Unrealized Gain (Loss) On Fair Value Of Warrants Unrealized (loss) gain on fair value of warrants Unrealized loss (gain) on fair value of warrants Other Nonoperating Income (Expense) Total Other (Loss) Income Income (Loss) from Continuing Operations Before Income Taxes, Domestic Net Loss Before Provision for Income Taxes Income Tax Expense (Benefit) Provision for Income Taxes Net Income (Loss) Attributable to Parent Net loss Net Loss Net Loss Income (Loss) from Continuing Operations, Per Basic Share Net loss per share, basic and diluted Weighted average number of common shares outstanding, basic and diluted Weighted average number of shares outstanding, basic and diluted Statement Of Comprehensive Loss [Abstract] Other Comprehensive Income (Loss), Unrealized Holding Gain (Loss) on Securities Arising During Period, Net of Tax Unrealized (loss) gain on available-for-sale securities Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive Loss Statement Of Stockholders' Equity [Abstract] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Common Stock [Member] Common Stock [Member] Additional Paid In Capital [Member] Additional Paid-in Capital [Member] Retained Earnings [Member] Accumulated Deficit [Member] Accumulated Other Comprehensive Income [Member] Accumulated Other Comprehensive Income (Loss) [Member] Stock Issued During Period, Value, New Issues Issuance of common stock and units, net of issuance costs Stock Issued During Period, Shares, New Issues Issuance of common stock and units, net of issuance costs, Shares Shares issued Stock Issued During Period, Value, Issued for Services Common stock issued in exchange for services Compensatory shares issued Common stock issued in exchange for services, shares Number of shares issued Number of Options, Exercised Stock options exercised, shares Stock Issued During Period, Shares, Conversion of Units Common stock issued from vested restricted stock units, shares Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Stock-based compensation Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Other Comprehensive income (loss) Statement Of Cash Flows [Abstract] Net Cash Provided by (Used in) Operating Activities [Abstract] Cash Flows from Operating Activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Issuance of Stock and Warrants for Services or Claims Compensatory stock Depreciation, Depletion and Amortization, Nonproduction Depreciation and amortization Gain (Loss) on Disposition of Property Plant Equipment Loss on sale of equipment Loss on sale of equipment Amortization Of Premiums And Discounts On Marketable Securities Amortization of premiums and discounts on marketable securities, net Share-based Compensation Stock-based compensation Amount of previously reported deferred research and development contribution that was recognized as expense during the period. Generally, an entity records deferred research and development contribution when it receives consideration from a collaborator, and expenses the contribution over a period of time. Amortization of Deferred Research and Development Contribution Amortization and termination of deferred research and development arrangement Increase (Decrease) in Operating Capital [Abstract] Changes in assets and liabilities: Increase (Decrease) in Prepaid, Deferred Expense, and Other Assets Prepaid expenses and other assets Increase (Decrease) In Accounts Payable and Accrued Liabilities Accounts payable and accrued expenses Increase (Decrease) in Deferred Revenue Deferred revenue Increase (Decrease) in Other Operating Assets and Liabilities, Net Other, net Net Cash Provided by (Used in) Operating Activities, Continuing Operations Net Cash Used in Operating Activities Net Cash Provided by (Used in) Investing Activities [Abstract] Cash Flows from Investing Activities: Payments to Acquire Machinery and Equipment Purchase of equipment Proceeds from Sale of Machinery and Equipment Sale of equipment Payments to Acquire Marketable Securities Purchase of marketable securities Proceeds from Sale and Maturity of Marketable Securities Redemption of marketable securities Net Cash Provided by (Used in) Investing Activities Net Cash Provided by (Used in) Investing Activities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash Flows from Financing Activities: Proceeds from Issuance of Common Stock Issuance of common stock and units, net of issuance costs Payments of Stock Issuance Costs Payment of deferred offering costs Net Cash Provided by (Used in) Financing Activities Net Cash Provided by Financing Activities Cash and Cash Equivalents, Period Increase (Decrease) Net Increase (Decrease) in Cash and Cash Equivalents Supplemental Cash Flow Information [Abstract] Supplemental Cash Flow Information Operating Lease, Payments Operating cash flows paid for amounts included in the measurement of lease liabilities Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Non-cash financing and investing activties: The fair value of common stock warrants issued during the period. Warrants issued Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Operating lease right-of-use assets obtained in exchange for lease obligations: Operations And Organization [Abstract] Nature of Operations [Text Block] Operations And Organization Summary of Significant Accounting Policies [Abstract] Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Marketable Securities [Abstract] Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Marketable Securities Prepaid Expenses And Other Current Assets [Abstract] The entire note disclosure regarding the Company's prepaid expenses and other current assets. These assets are primarily deposits on contracts but also includes other prepaid expenses such as rent, insurance, and investor relations services. Prepaid Expenses and Other Current Assets [Text block] Prepaid Expenses And Other Current Assets Equipment, Net [Abstract] Property, Plant and Equipment [Text Block] Equipment, Net Accounts Payable And Accrued Expenses [Abstract] Accounts Payable and Accrued Liabilities Disclosure Accounts Payable And Accrued Expenses Collaboration Agreement [Abstract] Collaboration and License Agreements [Abstract] Collaborative Arrangement Disclosure [Text Block] Collaboration and License Agreements Leases [Abstract] Lessee, Operating Leases [Text Block] Leases Net Loss Per Common Share [Abstract] Earnings Per Share [Text Block] Net Loss Per Common Share Common Stock [Abstract] Schedule of Stock by Class [Text Block] Common Stock Stock-Based Compensation [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Stock-Based Compensation Warrants [Abstract] Disclosure for warrants or rights issued. The Company's outstanding warrants and rights are non-derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable. Warrants [Text Block] Warrants Income Taxes [Abstract] Income Tax Disclosure [Text Block] Income Taxes Commitments And Contingencies [Abstract] Commitments and Contingencies Disclosure [Text Block] Commitments And Contingencies Fair Value Measurements [Abstract] Fair Value, Assets and Liabilities Measured on Nonrecurring Basis [Text Block] Fair Value Measurements Subsequent Event [Abstract] Subsequent Events [Text Block] Subsequent Event Nature of Operations [Policy Text Block] Nature of Operations [Policy Text Block] Operations Basis of Accounting, Policy [Policy Text Block] Basis Of Presentation Use of Estimates, Policy [Policy Text Block] Use of Estimates Reclassification, Policy [Policy Text Block] Reclassification Pandemic [Policy Text Block] Pandemic [Policy Text Block] COVID-19 Pandemic Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Marketable Securities, Policy [Policy Text Block] Marketable Securities Property, Plant and Equipment, Policy [Policy Text Block] Equipment Fair Value Measurement, Policy [Policy Text Block] Fair Value of Financial Instruments Warrants [Policy Text Block] Warrants [Policy Text Block] Warrants Research and Development Expense, Policy [Policy Text Block] Research and Development Income Tax, Policy [Policy Text Block] Income Taxes Compensation Related Costs, Policy [Policy Text Block] Stock-Based Compensation Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentration of Credit Risk New Accounting Pronouncements, Policy [Policy Text Block] Recent Accounting Pronouncements Affecting the Company Property, Plant and Equipment [Table Text Block] Schedule Of Equipment, Net Available-for-sale Securities [Table Text Block] Schedule Of Cost And Fair Value Of Marketable Securities Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block] Schedule Of Prepaid Expenses And Other Current Assets Tabular disclosure of the useful lives of each major class of property, plant and equipment. Schedule of Useful Lives of Property, Plant and Equipment [Table Text Block] Schedule Of Estimated Useful Lives Schedule of Accounts Payable and Accrued Liabilities [Table Text Block] Schedule Of Accounts Payable And Accrued Expenses Assets and Liabilities, Lessee [Table Text Block] Assets and Liabilities, Lessee [Table Text Block] Summary Of Right Of Use Lease Assets And Lease Liabilities Lease, Cost [Table Text Block] Components Of Lease Expense Lessee, Operating Lease, Liability, Maturity [Table Text Block] Scheduled Future Minimum Lease Payments Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Table Text Block] Summary Of Stock Compensation Expense Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule Of Assumptions Made In Calculating The Fair Value Of Options Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Summary Of Share-Based Transactions Schedule of Nonvested Share Activity [Table Text Block] Summary Of Unvested Shares Schedule of Share-based Compensation, Restricted Stock Units Award Activity [Table Text Block] Summary Of RSU Activity Summary Of Warrants Outstanding [Table Text Block] Summary Of Warrants Outstanding [Table Text Block] Summary Of Warrants Outstanding Summary Of Changes In Warrants Outstanding During The Period [Table Text Block] Summary Of Changes In Warrants Outstanding During The Period Schedule Of Fair Value Of Warrants Issued [Table Text Block] Schedule Of Fair Value Of Warrants Issued [Table Text Block] Schedule Of Fair Value Of Warrants Issued Schedule Of Assumptions Used In Calculating Fair Value Of Warrants [Table Text Block] Schedule Of Assumptions Used In Calculating Fair Value Of Warrants [Table Text Block] Schedule Of Assumptions Used In Calculating Fair Value Of Warrants Schedule Of Unrealized Gains Losses On Fair Value OF Warrants[Table Text Block] Schedule Of Unrealized Gains Losses On Fair Value OF Warrants [Table Text Block] Schedule Of Unrealized Gain/(Loss) On Fair Value Of Warrants Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Schedule Of Deferred Tax Assets And Valuation Allowance Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Schedule Of Assets And Liabilities Measured At Fair Value On A Recurring Basis Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block] Reconciliation Of Changes In The Fair Value Of Liabilities Cash, Cash Equivalents, and Short-term Investments Cash, cash equivalents and marketable securities New Accounting Pronouncements or Change in Accounting Principle [Table] New Accounting Pronouncements or Change in Accounting Principle [Line Items] Cash, Uninsured Amount Uninsured cash balance Schedule of Property, Plant and Equipment [Table] Range [Axis] Range [Member] Range [Domain] Minimum [Member] Minimum [Member] Maximum [Member] Maximum [Member] Property, Plant and Equipment, Type [Axis] Property Plant And Equipment Type [Domain] Property, Plant and Equipment, Type [Domain] Furniture And Fixtures [Member] Furniture and Fixtures [Member] Office Equipment [Member] Office Equipment [Member] Technology Equipment [Member] Lab equipment [Member] Computer Equipment [Member] Lab And Computer Equipment [Member] Leasehold Improvements [Member] Leasehold Improvements [Member] Property, Plant and Equipment [Line Items] Property, Plant and Equipment, Useful Life Life Property, Plant and Equipment, Depreciation Methods Depreciation Method Schedule of Available-for-sale Securities [Table] Investment Type [Axis] Investment Type Categorization [Member] Investments [Domain] Corporate Bond Securities [Member] Corporate Bonds [Member] Financial Instrument [Axis] Transfers And Servicing Of Financial Instruments Types Of Financial Instruments [Domain] Financial Instruments [Domain] Commercial Paper Not Included With Cash And Cash Equivalents [Member] Commercial Paper [Member] Schedule of Available-for-sale Securities [Line Items] Available-for-sale Securities, Amortized Cost Basis Cost Basis Available-for-sale Securities, Gross Unrealized Gain Gross Unrealized Gains Available-for-sale Securities, Gross Unrealized Losses Gross Unrealized Losses Available-for-sale Securities Fair Value Other Prepaid Expense, Current Deposits on contracts Other Assets, Current Prepaid expenses and other current assets Office And Computer Equipment [Member] Office And Computer Equipment [Member] Office And Computer Equipment [Member] Lab Equipment [Member] Lab Equipment [Member] Lab Equipment [Member] Property, Plant and Equipment, Gross Total equipment Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Less: Accumulated depreciation and amortization Accounts Payable, Trade Trade payables Accrued Liabilities Accrued expenses Other Accrued Liabilities Accrued research and development contract costs Employee-related Liabilities Payroll liabilities Accounts Payable and Accrued Liabilities Total accounts payable and accrued expenses Geographical [Axis] Segment Geographical [Domain] Geographical [Domain] C [N] China [Member] Republic of Singapore, China, Hong Kong, Macau and Taiwan [Member] Republic Of Singapore China Hong Kong Macau And Taiwan [Member] Republic of Singapore, China, Hong Kong, Macau and Taiwan [Member] Project [Axis] Project [Member] Project [Domain] BioSense Global LLC [Member] Biosense Global Llc [Member] BioSense Global LLC [Member] Zhejiang HaiChang Biotechnology Co., Ltd. [Member] Zhejiang Haichang Biotechnology Co. Ltd. [Member] Zhejiang HaiChang Biotechnology Co., Ltd. [Member] Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Research And Development Arrangement Contract To Perform For Others Type [Domain] Research and Development Arrangement, Contract to Perform for Others, Type [Domain] RX-3117 Development [Member] Rx3117 Development [Member] RX-3117 License [Member] RX-3117 Clinical Material [Member] Rx3117 Clinical Material [Member] RX-3117 Material [Member] RX-0201 [Member] Rx0201 [Member] RX-0201 [Member] RX-0047 [Member] Rx0047 [Member] RX-0047 [Member] Revenue from Contract with Customer, Including Assessed Tax Upfront payment Upfront Payment, Amount Received Upfront Payment, Amount Received Amount received from upfront payment Contract with Customer, Liability, Revenue Recognized Revenue recognized Billed Contracts Receivable Amount due Collaborative Arrangement, Milestone Payment Collaborative Arrangement, Milestone Payment Milestone payment Fixed Contingent Consideration Fixed Contingent Consideration Fixed consideration Research And Developement Agreement Period Research And Developement Agreement Period Research and development period Research And Developement Agreement Period Expense Reduction Amount Research And Developement Agreement Period Expense Reduction Amount Reduction of research and development expenses Research and Development Arrangement, Contract to Perform for Others, Compensation Earned Research and development arrangement, one-time fee Licensing Revenue Agreement Licensing Revenue Agreement Licensing revenue agreement Licensing Revenue Agreement, Percent Licensing Revenue Agreement, Percent Percentage of licensing revenue Lessee, Lease, Description [Table] Name of Property [Axis] Real Estate And Accumulated Depreciation Name Of Property [Domain] Name of Property [Domain] Prior Office Space Rental [Member] Prior Office Space Rental [Member] Prior Office Space Rental [Member] Office Space Rental [Member] Office Space Rental [Member] Office Space Rental [Member] Laboratory Lease [Member] Laboratory Lease [Member] Laboratory Lease [Member] Lessee, Lease, Description [Line Items] Area of Real Estate Property Area Lessee, Operating Lease, Discount Rate Discount rate Operating Lease, Weighted Average Remaining Lease Term Weighted average lease term Operating Lease, Cost Operating lease cost Variable Lease, Cost Variable lease cost Lease, Cost Lease expense Total Lease Cost Operating Lease, Liability Present value of minimum lease payments Lessee, Operating Lease, Liability, Payments, Remainder of Fiscal Year 2020 (excluding the three months ended March 31, 2020) Lessee, Operating Lease, Liability, Payments, Due Year Two 2020 Lessee, Operating Lease, Liability, Payments, Due Year Three 2021 Lessee, Operating Lease, Liability, Payments, Due Minimum lease payments Lessee, Operating Lease, Liability, Undiscounted Excess Amount Less: Imputed interest Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Securities [Axis] Antidilutive Securities Name [Domain] Antidilutive Securities, Name [Domain] Stock Options, Restricted Stock Units And Warrants [Member] Stock Options Restricted Stock Units And Warrants [Member] Stock Options, Restricted Stock Units And Warrants [Member] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Potentially dilutive securities Schedule of Stock by Class [Table] Class of Warrant or Right [Axis] Class Of Warrant Or Right [Domain] Class of Warrant or Right [Domain] Warrants To Placement Agent [Member] Warrants To Placement Agent [Member] Placement Agent Warrant [Member] Class of Stock [Line Items] Stockholders' Equity Note, Stock Split, Conversion Ratio Reverse stock split Investment Warrants, Issued, Number Investment Warrants, Issued, Number Number of warrants, issued Warrants issued Warrants issued per share of stock issued in unit offering Warrants issued per share of stock issued in unit offering Proceeds From Issuance Of Common Stock, Gross Proceeds From Issuance Of Common Stock, Gross Proceeds from issuance Share Price Share price Class of Warrant or Right, Exercise Price of Warrants or Rights Warrants exercise price Exercise Price Warrants Issued Included In Closing Costs Warrants Issued Included In Closing Costs Warrants issued included in closing costs Public Offering Closing Costs Public Offering Closing Costs Public offering closing costs Placement Agent Warrants, Fair Value At Issuance Placement Agent Warrants, Fair Value At Issuance Fair value of placement agent warrants Cash paid in exchange for legal services and closing costs. Cash Paid In Exchange For Legal Services Cash paid in exchange for legal services Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Exercise Price Range [Axis] Share Based Compensation Shares Authorized Under Stock Option Plans Exercise Price Range [Domain] Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range [Domain] Exercise Price Range B [Member] Exercise Price Range B [Member] Exercise Price Range $5.23 to $7.45 [Member] Exercise Price Range C [Member] Exercise Price Range C [Member] Exercise Price Range $13.08 to $27.48 [Member] Vesting [Axis] Vesting [Domain] Vesting [Domain] Share Based Compensation Award Tranche One [Member] Share-based Compensation Award, Tranche One [Member] Share Based Compensation Award Tranche Two [Member] Share-based Compensation Award, Tranche Two [Member] Plan Name [Axis] Plan Name [Domain] Plan Name [Domain] Information related to the 2013 stock option plan. The2013 Plan [Member] The 2013 Plan [Member] Information related to the 2003 stock option plan. The2003 Plan [Member] The 2003 Plan [Member] Award Type [Axis] Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Equity Award [Domain] Employee Stock Option [Member] Stock Option [Member] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Number of Options, Oustanding Number of Options, Oustanding Number of options outstanding Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized Options authorized for issuance Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Vesting period Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period Percentage Vesting percentage Percentage of Event Occurence to Vest Percentage of Event Occurence to Vest Share Based Compensation Arrangement By Share Based Payment Award Expiration Date Range Share Based Compensation Arrangement By Share Based Payment Award Expiration Date Range Expiration of options from grant date, years Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Shares available for issuance Other Tax Expense (Benefit) Income tax benefit from share-based compensation Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Stock options granted Number of Options, Granted Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Stock option exercise price Weighted Average Exercise Price, Granted Percentage of deferred tax assets for which it is more likely than not that a tax benefit will not be realized. Deferred Tax Assets Valuation Allowance Percentage Valuation allowance on deferred tax assets Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Grant Date Fair Value Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Grant Date Fair Value Stock option grants fair value Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Total Intrinsic Value Intrinsic value of options exercised The weighted average fair value of awards vested during the period on option plans. Share Based Compensation Arrangement By Share Based Payment Award Options Vested, Weighted Average Grant Date Fair Value Weighted average fair value at grant date, Vested Employee Service Share-based Compensation, Nonvested Awards, Total Compensation Cost Not yet Recognized Unrecognized compensation cost Employee Service Share-based Compensation, Nonvested Awards, Total Compensation Cost Not yet Recognized, Period for Recognition Weighted average vesting period, years Schedule of Share-based Compensation, Allocation of Recognized Period Costs [Table] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] General and administrative, Payroll [Member] General And Administrative Payroll [Member] General and administrative [Member] Research and development, Consulting and other professional fees [Member] Research And Development Consulting And Other Professional Fees [Member] Research and development [Member] Share-based Compensation, Allocation of Recognized Period Costs [Line Items] Allocated Share-based Compensation Expense Share Based Compensation Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum Expected volatility, minimum Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Expected volatility, maximum Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Risk-free interest rate, minimum Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Risk-free interest rate, maximum Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Expected term (in years) Share-based Compensation Arrangement by Share-based Payment Award, Options, Expirations in Period Number of Options, Expired Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Number of Options, Cancelled Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted Average Exercise Price, Outstanding Weighted Average Exercise Price, Outstanding Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Exercised Share-based Compensation Arrangements by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Expired Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Cancelled Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Weighted Average Remaining Contractual Term, Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Aggregate Intrinsic Value, Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Number of Options, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Weighted Average Exercise Price, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Weighted Average Remaining Contractual Term, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value Aggregate Intrinsic Value, Exercisable Schedule of Deferred Compensation Arrangement with Individual, Share-based Payments [Table] Type of Deferred Compensation [Axis] Equity Based Arrangements Individual Contracts Type Of Deferred Compensation [Domain] Equity-Based Arrangements, Individual Contracts, Type of Deferred Compensation [Domain] Nonvested Options [Member] Nonvested Options [Member] Nonvested Options [Member] Deferred Compensation Arrangement with Individual, Share-based Payments [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares Number of Options, Unvested Number of Options, Unvested Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Number of Shares Number of Options, Vested Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested Options Forfeited, Number of Shares Number of Options, Cancelled Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Weighted Average Grant Date Fair Value Weighted Average Fair Value at Grant Date, Unvested Weighted Average Fair Value at Grant Date, Unvested Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted Average Fair Value at Grant Date, Granted Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value Weighted Average Fair Value at Grant Date, Vested Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested Options Forfeited, Weighted Average Grant Date Fair Value Weighted Average Fair Value at Grant Date, Cancelled Restricted Stock Units R S U [Member] Restricted Stock Units (RSUs) [Member] Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number Number of RSUs, Outstanding Number of RSUs, Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period Number of RSUs, Granted Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period Number of RSUs, Vested and Released Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period Number of RSUs, Cancelled Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Outstanding Weighted Average Grant Date Fair Value, Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Granted Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Vested and Released Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Cancelled Class of Warrant or Right [Table] Class of Warrant or Right [Line Items] Investment Warrants Weighted Average Remaining Contractual Term Investment Warrants Weighted Average Remaining Contractual Term Average remaining contractual life of warrants outstanding Date I Warrants To Institutional Investors [Member] Date I Warrants To Institutional Investors [Member] January 2014 Investor Warrants [Member] Date C Warrants To Institutional Investors [Member] Date C Warrants To Institutional Investors [Member] November 2015 Investor Warrants [Member] Date B Warrants To Placement Agent [Member] Date B Warrants To Placement Agent [Member] November 2015 Placement Agent Warrants [Member] Date J Warrants To Institutional Investors [Member] Date J Warrants To Institutional Investors [Member] March 2016 Investor Warrants [Member] Date D Warrants To Institutional Investors [Member] Date D Warrants To Institutional Investors [Member] September 2016 Investor Warrants [Member] Date K Warrants To Institutional Investors [Member] Date K Warrants To Institutional Investors [Member] June 2017 Investor Warrants [Member] Date F Warrants To Placement Agent [Member] Date F Warrants To Placement Agent [Member] June 2017 Placement Agent Warrants [Member] Date L Warrants To Institutional Investors [Member] Date L Warrants To Institutional Investors [Member] October 2017 Investor Warrants [Member] Date G Warrants To Placement Agent [Member] Date G Warrants To Placement Agent [Member] October 2017 Placement Agent Warrants [Member] Date F Warrants To Institutional Investors [Member] Date F Warrants To Institutional Investors [Member] October 2018 Investor Warrants [Member] Date J Warrants To Placement Agent [Member] Date J Warrants To Placement Agent [Member] October 2018 Placement Agent Warrants [Member] Date G Warrants To Institutional Investors [Member] Date G Warrants To Institutional Investors [Member] January 2019 Investor Warrants [Member] Liability-Classified Warrants [Member] Liability Classified Warrants [Member] Liability-Classified Warrants [Member] Equity-Classified Warrants [Member] Equity Classified Warrants [Member] Equity-Classified Warrants [Member] Class of Warrant or Right, Outstanding Number of warrants, Outstanding Number of warrants, Outstanding Number of Warrants Class of Warrant or Right, Expiration Date Class of Warrant or Right, Expiration Date Expiration Date Investment Warrants, Exercised, Number Investment Warrants, Exercised, Number Number of warrants, Exercised Investment Warrants, Expired, Number Investment Warrants, Expired, Number Number of warrants, Expired Warrants Exercise Price Warrants Exercise Price Weigted average exercise price, Outstanding Weigted average exercise price, Outstanding Investment Warrants, Issued, Weighted Average Exercise Price Investment Warrants, Issued, Weighted Average Exercise Price Weighted average exercise price, Issued Investment Warrants, Exercised, Weighted Average Exercise Price Investment Warrants, Exercised, Weighted Average Exercise Price Weighted average exercise price, Exercised Investment Warrants, Expired, Weighted Average Exercise Price Investment Warrants, Expired, Weighted Average Exercise Price Weighted average exercise price, Expired Investment Warrants, Fair Value Investment Warrants, Fair Value Fair value Investment Warrants, Fair Value Assumptions, Trading Market Prices Investment Warrants, Fair Value Assumptions, Trading Market Prices Trading market prices Investment Warrants Fair Value Assumptions Estimated Future Volatility Rate Investment Warrants Fair Value Assumptions Estimated Future Volatility Rate Estimated future volatility Investment Warrants, Fair Value Assumptions, Estimated Dividend Investment Warrants, Fair Value Assumptions, Estimated Dividend Dividend Investment Warrants, Fair Value Assumptions, Risk Free Interest Rate Investment Warrants, Fair Value Assumptions, Risk Free Interest Rate Estimated future risk-free rate Investment Warrants, Fair Value Assumptions, Equivalent Volatility Rate Investment Warrants, Fair Value Assumptions, Equivalent Volatility Rate Equivalent volatility Investment Warrants, Fair Value Assumptions, Equivalent Risk Free Rate Investment Warrants, Fair Value Assumptions, Equivalent Risk Free Rate Equivalent risk-free rate Investment Warrants, Fair Value Assumptions, Estimated Additional Shares Issued Upon Dilutive Event Investment Warrants, Fair Value Assumptions, Estimated Additional Shares Issued Upon Dilutive Event Fundamental transaction likelihood Warrant Fundamental Transaction Timing, Date Warrant Fundamental Transaction Timing, Date Fundamental transaction timing Warrant Fundamental Transaction Timing, Description Warrant Fundamental Transaction Timing, Description Fundamental transaction timing Expired Warrants [Member] Expired Warrants [Member] Expired Warrants [Member] Operating Loss Carryforwards [Table] Income Tax Authority [Axis] Income Tax Authority [Domain] Income Tax Authority [Domain] Federal And State [Member] Federal And State [Member] Federal And State [Member] Operating Loss Carryforwards [Line Items] Operating Loss Carryforwards Operating loss carry-forward Operating Loss Carryforwards, Expiration Dates Net operating loss carry-forwards expiration Deferred Tax Assets, Operating Loss Carryforwards Net Operating Loss Carryforwards Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-based Compensation Cost Stock Compensation Expense Deferred Tax Assets Book Tax Differences On Assets And Liabilities Deferred Tax Assets Book Tax Differences On Assets And Liabilities Book Tax Differences on Assets and Liabilities Deferred Tax Assets, Valuation Allowance Valuation Allowance Deferred Tax Assets, Net of Valuation Allowance Net Deferred Tax Assets Commitments And Contingencies [Table] Commitments And Contingencies [Table] Commitments And Contingencies [Line Items] Commitments And Contingencies [Line Items] Research And Developement Arragement Contract To Perform For Others, Term Research And Developement Arragement Contract To Perform For Others, Term Contract term, months Research and development agreements, estimated cost to complete contracts with vendors Research and development, estimated cost to complete contracts with vendors Estimated cost to complete contracts Research And Developement Agreement One Time Milestone Payment Research And Developement Agreement One Time Milestone Payment One-time milestone payment First achievement of marketing approvals First achievement of marketing approvals Defined Contribution Plan, Employer Matching Contribution Defined Contribution Plan, Employer Matching Contribution Employer matching contribution Defined Contribution Plan, Maximum Annual Contribution Per Employee, Percent Maximum percentage of employee's gross pay Defined Contribution Plan Maximum Annual Contribution Per Employee Additional Percent On Deferral Defined Contribution Plan Maximum Annual Contribution Per Employee Additional Percent On Deferral Employer matching contribution on deferral Defined Contribution Plan, Employer Matching Contribution, Percent Percentage of employee's gross pay Defined Contribution Plan, Cost Recognized Expense related to matching contribution Research and Development Arrangement, Licensing Revenue Percentage Research and Development Arrangement, Licensing Revenue Percentage Royalty Research and Development Arrangement, Licensing Revenue Research and Development Arrangement, Licensing Revenue Licensing revenue Fair Value, Assets, Level 1 to Level 2 Transfers, Amount Fair Value, Assets, Level 2 to Level 1 Transfers, Amount Fair Value, Liabilities, Level 1 to Level 2 Transfers, Amount Fair Value, Liabilities, Level 2 to Level 1 Transfers, Amount Fair Value Measurements, Recurring and Nonrecurring [Table] Fair Value, Hierarchy [Axis] Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value, Measurements, Fair Value Hierarchy [Domain] Fair Value Inputs Level1 [Member] Level 1 [Member] Fair Value Inputs Level2 [Member] Level 2 [Member] Fair Value Inputs Level3 [Member] Level 3 [Member] Cash and Cash Equivalents [Axis] Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member] Cash and Cash Equivalents [Domain] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Assets, Fair Value Disclosure Total Assets: Financial and Nonfinancial Liabilities, Fair Value Disclosure Warrant Liabilities Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Liability Class [Axis] Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation By Liability Class [Domain] Fair Value by Liability Class [Domain] Warrant Liabilities [Member] Warrant Liabilities [Member] Warrant Liabilities [Member] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Fair Value, Measurement with Unobservable Inputs Reconciliations, Recurring Basis, Liability Value Balance Balance Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Unrealized (Gains) Losses Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Unrealized (Gains) Losses Unrealized losses, net Subsequent Event [Table] RX-0201 And RX-0301 [Member] Rx0201 And Rx0301 [Member] RX-0201 And RX-0301 [Member] Subsequent Event [Line Items]