X0508 4 2026-01-22 0001228627 Opus Genetics, Inc. IRD 0002008983 Jayagopal Ashwath C/O OPUS GENETICS, INC. 8 DAVIS DRIVE, SUITE 220 DURHAM NC 27713 true Chief Scientific & Dev. Ofc. false Common Stock 2026-01-22 4 A 0 400000 0 A 525807 D Represents a grant of restricted stock units which vest in substantially equal quarterly installments on the anniversary of the grant date over the next sixteen (16) quarters, subject to the Reporting Person's continuing service. /s/ Amy Rabourn, by Power of Attorney 2026-01-26