X0508 4 2025-04-30 0001228627 Opus Genetics, Inc. IRD 0001373649 Benton Susan C/O OPUS GENETICS, INC. 8 DAVIS DRIVE, SUITE 220 DURHAM NC 27709 true false Common Stock 2025-04-30 4 A 0 79504 0 A 219527 D Stock Option (Right to Buy) 0.95 2025-04-30 4 A 0 79592 0 A 2035-04-29 Common Stock 79592 79592 D Represents a grant of restricted stock units which vest upon the earlier of the one (1) year anniversary of the grant date or the day prior to the Issuer's next annual meeting of stockholders occurring after the grant date, subject to the Reporting Person's continuing service through the vesting date. The option will vest upon the earlier of the one (1) year anniversary of the grant date or the day prior to the Issuer's next annual meeting of stockholders occurring after the grant date, subject to the Reporting Person's continuing service through the vesting date. /s/ Amy Rabourn, by Power of Attorney 2025-05-02