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Income Taxes - Schedule of Reconciliation of Statutory Federal Income Tax Rate (Details)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Income Tax Disclosure [Abstract]      
U.S. federal statutory income tax rate 21.00% 21.00% 21.00%
State and local taxes, net of federal benefit 3.50% 4.40% 3.80%
Nondeductible expenses (0.80%) 6.40% 0.70%
Research and development credits 0.00% (0.70%) 0.60%
Tax rate change and true-up (1.60%) 0.00% 0.60%
Change in valuation allowance (22.10%) (31.10%) (26.70%)
Effective income tax rate 0.00% 0.00% 0.00%