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Debt - Additional Information (Details)
3 Months Ended 9 Months Ended
Mar. 02, 2020
USD ($)
Tranche
Event
Feb. 29, 2020
USD ($)
Sep. 30, 2020
USD ($)
Sep. 30, 2019
USD ($)
Sep. 30, 2020
USD ($)
Sep. 30, 2019
USD ($)
Mar. 31, 2017
USD ($)
Debt Instrument [Line Items]              
Interest expense     $ 1,000,000.0 $ 900,000 $ 3,500,000 $ 2,800,000  
Cash interest expense     800,000 700,000 3,100,000 2,200,000  
Non-cash interest expense     200,000 $ 200,000 $ 400,000 $ 600,000  
Solar Capital Ltd | Term A Loan and Term B Loan              
Debt Instrument [Line Items]              
Basis spread on variable rate 1.66%            
Interest rate 7.65%            
Interest-only period 2022-03            
Interest-only period upon achievement of revenues 2023-02            
Number of default events | Event 0            
Line of credit facility, conversion to term loan, conditions         At the Company’s election, the interest only period may be extended through February 2023 if the Company satisfies a minimum net product revenue covenant through March 1, 2022 and no event of default shall have occurred    
Solar Capital Ltd | $35.0 Million Credit Facility              
Debt Instrument [Line Items]              
Line of credit facility, maximum borrowing capacity             $ 35,000,000.0
Solar Capital Ltd | $35.0 Million Credit Facility | Term A Loan              
Debt Instrument [Line Items]              
Borrowings outstanding under credit facility $ 35,000,000.0            
Solar Capital Ltd | $50.0 Million Credit Facility              
Debt Instrument [Line Items]              
Line of credit facility, maximum borrowing capacity $ 50,000,000.0            
Term loans number of tranches | Tranche 2            
Increase in final payment fees percentage upon extension interest only periods 5.50%            
Trailing twelve month net product revenue first threshold limit to pay exit fee $ 100,000,000            
Trailing twelve month net product revenue Second threshold limit to pay exit fee $ 125,000,000            
Percentage of exit fee for liquidation, dissolution, winding up or change of control of the Company 4.50%            
Percentage of exit fee upon achievement of any trailing twelve month revenues 2.25%            
Percentage of exit fee upon achievement of both trailing twelve month revenues 4.50%            
Capped exit fee percentage on term loan principal amount 4.50%            
Solar Capital Ltd | $50.0 Million Credit Facility | Prepaid on or Before First Anniversary of Funding              
Debt Instrument [Line Items]              
Prepayment fees percentage 3.00%            
Solar Capital Ltd | $50.0 Million Credit Facility | Prepaid After First and on or Before Second Anniversary of Funding              
Debt Instrument [Line Items]              
Prepayment fees percentage 2.00%            
Solar Capital Ltd | $50.0 Million Credit Facility | Prepaid After Second Anniversary of Funding              
Debt Instrument [Line Items]              
Prepayment fees percentage 1.00%            
Solar Capital Ltd | $50.0 Million Credit Facility | Term A Loan              
Debt Instrument [Line Items]              
Credit facility maturity date Feb. 28, 2025            
Solar Capital Ltd | $15 Million Credit Facility | Term B Loan              
Debt Instrument [Line Items]              
Line of credit facility, maximum borrowing capacity $ 15,000,000.0            
Line of credit facility, conversion to term loan, conditions         Under the Term B Loan portion of the Solar Facility, the Company is permitted to borrow, at its election, up to an aggregate amount of $15.0 million, (i) upon the Company achieving a specified amount of trailing twelve months net product revenue, and (ii) assuming there has been no event of default under the Solar Facility prior to such election. Once the net product revenue condition has been satisfied, the Company may only make an election to borrow under the Term B Loan portion of the Solar Facility until the earlier of (a) December 15, 2021, (b) 30 days following achievement of the net product revenue condition or (c) the occurrence of an event of default.    
Oxford Finance LLC | $35.0 Million Credit Facility              
Debt Instrument [Line Items]              
Line of credit facility, maximum borrowing capacity   $ 35,000,000.0 35,000,000.0   $ 35,000,000.0    
Borrowings outstanding under credit facility     $ 35,000,000.0   $ 35,000,000.0    
Credit facility maturity date         Feb. 01, 2025    
Debt instrument, interest rate     8.15%   8.15%    
Debt instrument, final payment fee         $ 2,500,000    
Combined debt discount and deferred issuance costs     $ 600,000   $ 600,000    
Oxford Finance LLC | $35.0 Million Credit Facility | LIBOR              
Debt Instrument [Line Items]              
Basis spread on variable rate         7.38%    
Debt instrument, description of variable rate basis         30 day U.S. LIBOR    
Oxford Finance LLC | $35.0 Million Credit Facility | Term A Loan              
Debt Instrument [Line Items]              
Borrowings outstanding under credit facility   $ 25,000,000          
Final payment fees percentage   8.50%          
Oxford Finance LLC | $35.0 Million Credit Facility | Term B Loan              
Debt Instrument [Line Items]              
Borrowings outstanding under credit facility   $ 5,000,000.0          
Final payment fees percentage   7.50%          
Oxford Finance LLC | $35.0 Million Credit Facility | Term C Loan              
Debt Instrument [Line Items]              
Line of credit facility, current borrowing capacity   $ 5,000,000.0