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Description of Business - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Dec. 31, 2018
Description Of Business [Line Items]      
Cash and cash equivalents $ 96,146   $ 104,583
Accumulated deficit 228,572   221,043
Cash flows from operating activities 9,570 $ 8,297 $ 20,600
$35.0 Million Credit Facility | Oxford Finance LLC      
Description Of Business [Line Items]      
Borrowings outstanding under credit facility $ 30,000    
Credit facility maturity date Mar. 01, 2022