Exhibit 16.1

March 3, 2020

Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549-7561

Dear Sirs/Madams:

We have read Item 4.01 of NeoPhotonics Corporation’s Form 8-K dated March 3, 2020, and have the following comments:

1. We are in agreement with the statements made in paragraphs one through five of Item 4.01(a).

2. We have no basis on which to agree or disagree with other statements made therein.

Yours truly,

/s/ Deloitte & Touche LLP