The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number:3235-0006
Expires:Oct 31, 2018
Estimated average burden
hours per response:23.8

COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ABBOTT LABSCOM28241001203,040SH SOLE 000
ABBVIE INCCOM00287Y109771,250SH SOLE 000
ABEONA THERAPEUTICS INC*W EXP 12/19/20100289Y1151,0711,259,636SH SOLE 000
Abeona Therapeutics IncCOM00289Y1074,1591,762,881SH SOLE 000
ABIOMED INCCOM36541001,60714,700SH SOLE 000
ACADIA PHARMACEUTICALS INCCOM42251085,364165,240SH SOLE 000
ACASTI PHARMA INCCL A NEW00430K402336236,559SH SOLE 000
ACCELERONCOM00434H10820,491603,036SH SOLE 000
ACELRX PHARMACOM00444T10016,1295,995,760SH SOLE 000
ADMA BIOLOGICS INCCOM8991042,371398,394SH SOLE 000
AEGLEA BIOTHERAPEUTICS INCCOM00773J103515105,893SH SOLE 000
AETNA INC NEWCOM00817Y1085444,454SH SOLE 000
AFFIMED N VCOMN010451081,821734,301SH SOLE 000
AGILE THERAPEUTICS INCCOM00847L1003,914514,288SH SOLE 000
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AKEBIA THERAPEUTICS INCCOM00972D1056,684893,600SH SOLE 000
ALCOBRA LTDSHSM2239P1094,6171,028,272SH SOLE 000
ALDER BIOPHARMACEUTICALS INCCOM143391059,988400,000SH SOLE 000
ALDEYRACOM01438T10611,0411,940,458SH SOLE 000
ALLIQUA BIOMEDICAL INCCOM NEW196212002,1521,921,951SH SOLE 000
ALLON THERAPEUTICSCOM0197741080751,124SH SOLE 000
ALMOST FAMILY INCCOM2040910850911,942SH SOLE 000
AMERISOURCEBERGEN CORPCOM03073E1055166,500SH SOLE 000
AMICUSCOM03152W10983,20715,239,444SH SOLE 000
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ANI PHARMACEUTICALS INCCOM00182C1033,74967,161SH SOLE 000
ANI PHARMACEUTICALS INCNOTE 3.000%12/00182CAA18,1217,500,000PRN SOLE 000
ANTHEM INCCOM367521034473,400SH SOLE 000
ANTHERA PHARMACEUTICALS INCCOM NEW03674U2014,6111,492,156SH SOLE 000
APPLIED GENETIC TECHNOL CORPCOM03820J1009,309658,851SH SOLE 000
ARATANA THERAPEUTICS INCCOM03874P1011,621256,500SH SOLE 000
ARDELYX INCCOM396971072,758315,955SH SOLE 000
ARNO THERAPEUTIC INCCOM425642031,0803,463,292SH SOLE 000
ASSEMBLY BIOSCIENCES INCCOM453961084,412795,000SH SOLE 000
ATARA BIOTHERAPEUTICS INCCOM46513107562,500SH SOLE 000
AVEO PHARMACEUTICALS INCCOM0535881092,9873,108,808SH SOLE 000
AVEXIS INCCOM05366U100581,515SH SOLE 000
AVINGER INCCOM53734109131,062SH SOLE 000
AXOVANT SCIENCES LTDCOMG0750W1046,227485,000SH SOLE 000
BIOTIME INCCOM09066L1053613,740SH SOLE 000
BLUEPRINT MEDICINES CORPCOM09627Y1099,404464,404SH SOLE 000
BRAINSTROM CELL THERAPEUTICSCOM10501E201964400,000SH SOLE 000
CAPITAL SR LIVING CORPCOM14047510410,357586,136SH SOLE 000
CAPRICOR THERAPEUTICS INCCOM14070B101164,000SH SOLE 000
CARDINAL HEALTH INCCOM14149Y1084996,398SH SOLE 000
Cascadian Therapeutics IncCOM14740B1013,2203,414,121SH SOLE 000
CELATOR PHARMACEUTICALS INCCOM15089R10225,303838,400SH SOLE 000
CELLDEX THERAPEUTICS INC NEWCOM15117B10331271,124SH SOLE 000
CELLECTIS S ASPONSORED ADS15117K1034,879183,507SH SOLE 000
CEMPRA INCCOM15130J1092,803170,000SH SOLE 000
CENTENE CORP DELCOM15135B1013534,948SH SOLE 000
CHAMPIONS ONCOLOGY INCCOM NEW15870P307801372,597SH SOLE 000
CHARLES RIV LABS INTL INCCOM1598641074525,482SH SOLE 000
CHINA BIOLOGIC PRODS INCCOM16938C1061,48814,000SH SOLE 000
CIDARA THERAPEUTICS INCCOM1717571078,174792,857SH SOLE 000
CLEARSIDE BIOMEDICAL INCCOM1850631044,450634,808SH SOLE 000
COGENTIX MED INCCOM19243A104498517,760SH SOLE 000
CORBUS PHARMACEUTICALS HLDGSCOM21833P1039,5683,200,000SH SOLE 000
CORCEPT THERAPEUTICS INCCOM2183521026011,000SH SOLE 000
CYTOMX THERAPEUTICS INCCOM23284F1057,579742,021SH SOLE 000
DBV TECHNOLOGIES S ASPONSORED ADR23306J10117,833546,696SH SOLE 000
DEPOMED INCCOM24990810411,727600,000SH SOLE 000
DERMA SCIENCES INCCOM PAR $.012498275021,706432,884SH SOLE 000
DERMIRA INCCOM24983L10413,514462,000SH SOLE 000
DEXCOM INCCOM2521311079,930125,174SH SOLE 000
DIGIRAD CORPCOM25382710912924,988SH SOLE 000
DIPLOMAT PHARMACY INCCOM25456K101762,175SH SOLE 000
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EAGLE PHARMACEUTICALS INCCOM26979610811,637300,000SH SOLE 000
EIGER BIOPHARMACEUTICALS INCCOM28249U1052,079104,920SH SOLE 000
ENZO BIOCHEM INCCOM29410010240167,113SH SOLE 000
EVOLENT HEALTH INCCL A30050B10116,763873,064SH SOLE 000
FERRARI N VCOMN3167Y1032546,200SH SOLE 000
FIAT CHRYSLER AUTOMOBILES NSHSN3173810237962,000SH SOLE 000
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FLEX PHARMA INCCOM33938A1052237SH SOLE 000
FOAMIX PHARMACEUTICALS LTDSHSM461351055,048795,000SH SOLE 000
FORWARD PHARMA A/SSPONSORED ADR34986J1055,658311,400SH SOLE 000
GENOCEA BIOSCIENCES INCCOM3724271047117,313SH SOLE 000
GENVEC INCCOM NEW37246C3073,447606,644SH SOLE 000
GLAUKOS CORPCOM3773221029300SH SOLE 000
GLOBAL BLOOD THERAPEUTICS INCOM37890U10836,6252,207,668SH SOLE 000
GLOBUS MED INCCL A3795772081,19250,000SH SOLE 000
HCA HOLDINGS INCCOM40412C1014786,202SH SOLE 000
HERBALIFE LTDCOM USD SHSG4412G101731,250SH SOLE 000
IGNYTA INCCOM4517311032,359435,260SH SOLE 000
IMMUNOGEN INCCOM45253H1017925,745SH SOLE 000
IMMUNOMEDICS INCCOM452907108514221,700SH SOLE 000
INNOCOLL HLDGS PLCSHSG4783X1052,808560,000SH SOLE 000
INOGEN INCCOM45780L1046125SH SOLE 000
INTELLIA THERAPEUTICS INCCOM45826J10532015,000SH SOLE 000
Ionis Pharmaceuticals Ord ShsCOM4622221002,329100,000SHPutSOLE 000
JUNO THERAPEUTICS INCCOM48205A109431,113SH SOLE 000
KINDRED HEALTHCARE INCCOM49458010347842,301SH SOLE 000
LA JOLLA PHARMACEUTICAL COCOM PAR $.0001 250345960421,3251,332,815SH SOLE 000
LABORATORY CORP AMER HLDGSCOM NEW50540R4095203,990SH SOLE 000
LANNET INCCOM51601210163426,670SH SOLE 000
Lexicon Pharmaceuticals IncCOM52887230271850,000SH SOLE 000
LION BIOTECHNOLOGIES INCCOM53619R10229,2573,611,976SH SOLE 000
LIPOCINE INCCOM53630X104865284,400SHPutSOLE 000
LIPOCINE INCCOM53630X104912300,000SHCallSOLE 000
MAGELLAN HEALTH INCCOM NEW5590792075778,772SH SOLE 000
MCKESSON CORPCOM58155Q1035562,979SH SOLE 000
MEDGENICS INCCOM NEW58436Q2031,665300,000SH SOLE 000
MEDIVATION INCCOM58501N10145,828760,000SH SOLE 000
MERRIMACK PHARMACEUTICALS INCOM59032810027050,000SH SOLE 000
MGC DIAGNOSTICS CORPCOM5527681032,193336,287SH SOLE 000
MINERVA NEUROSCIENCES INCCOM6033801068,275810,537SH SOLE 000
MOLINA HEALTHCARE INCCOM60855R1004599,200SH SOLE 000
MYLAN N VSHS EURON594651092165,000SH SOLE 000
MYOKARDIA INCCOM62857M1056,235502,894SH SOLE 000
NEOS THERAPEUTICS INCCOM64052L1064,611626,876SH SOLE 000
NEPTUNE TECHNOLOGIES BIORESOCOM64077P1086,8856,750,444SH SOLE 000
NEUROCRINE BIOSCIENCES INCCOM64125C109127,1672,797,967SH SOLE 000
NEURODERM LTDORD SHSM742311074,388270,000SH SOLE 000
NEVRO CORPCOM64157F10326,939365,229SH SOLE 000
NIVALIS THERAPEUTICS INCCOM65481J109575125,000SH SOLE 000
NOVAVAX INCCOM67000210423332,000SH SOLE 000
NXSTAGE MEDICAL INCCOM67072V10329,9711,382,410SH SOLE 000
ONCOBIOLOGICS INCCOM68235M1054,4631,312,763SH SOLE 000
ONCOBIOLOGICS INC*W EXP 02/18/20168235M113212462,500SH SOLE 000
ONCOBIOLOGICS INC*W EXP 05/18/20168235M121202462,500SH SOLE 000
OPHTHOTECH CORPCOM6837451034168,145SH SOLE 000
PEREGRINE PHARMACEUTICALS INCOM NEW71366130481224,332SH SOLE 000
PERNIX THERAPEUTICS HLDGS INDBCV 4.250% 4/071426VAK42001,000,000PRN SOLE 000
PFENEX INCCOM7170711048,043960,877SH SOLE 000
PHASERX INCCOM71723F103852200,000SH SOLE 000
PHIBRO ANIMAL HEALTH CORPCL A COM71742Q10645324,300SH SOLE 000
PROGENICS PHARMACEUTICALSCOM7431871062,110500,000SHPutSOLE 000
PROTEON THERAPEUTICS INCCOM74371L1092,208275,000SH SOLE 000
PROTEOSTASIS THERAPEUTICS INCOM74373B1093,033250,000SH SOLE 000
pSivida CorpCOM74440J1017,5422,665,000SH SOLE 000
QUOTIENT LTDSHSG7326810717,4302,249,067SH SOLE 000
REGENXBIO INCCOM75901B1078,7931,099,213SH SOLE 000
RELYPSA INCCOM7595311061,850100,000SHPutSOLE 000
Retrophin IncCOM76129910658,4053,279,380SH SOLE 000
Sarepta Therapeutics IncCOM803607100145,3007,619,300SHPutSOLE 000
Sarepta Therapeutics IncCOM80360710018,673979,200SHCallSOLE 000
SAREPTA THERAPEUTICS INCCOM80360710071,8433,767,316SH SOLE 000
SCYNEXIS INCCOM811292101380175,000SH SOLE 000
SELECTA BIOSCIENCES INCCOM8162121046,296450,000SH SOLE 000
SERES THERAPEUTICS INCCOM81750R102451,540SH SOLE 000
SEVION THERAPEUTICSCOM81834Q1041259,220SH SOLE 000
ST JUDE MEDICALCOM79084910318,174233,000SH SOLE 000
STEMLINE THERAPEUTICS INCCOM85858C10753278,603SH SOLE 000
STREETTRACKS SPDR BIOTEC ETFS&P BIOTECH78464A87027,045500,000SHPutSOLE 000
SUCAMPO PHARMACEUTICALS INCCL A86490910645141,096SH SOLE 000
SUPERNUS PHARMACEUTICALS INCCOM8684591085,093250,000SH SOLE 000
TENET HEALTHCARE CORPCOM NEW88033G40744816,200SH SOLE 000
TENGION INCCOM88034G20811,826,399SH SOLE 000
TESARO INCCOM8815691074,20350,000SHPutSOLE 000
TESARO INCCOM88156910796,1211,143,615SH SOLE 000
TEVA PHARMACEUTICAL INDS LTDADR8816242099,845196,000SH SOLE 000
TOKAI PHARMACEUTICALS INCCOM88907J1073,642661,041SH SOLE 000
UNIQURE NVSHSN900641019,8911,342,093SH SOLE 000
UNITED THERAPEUTICS CORP DELCOM91307C1025034,753SH SOLE 000
UNITEDHEALTH GROUP INCCOM91324P1024563,231SH SOLE 000
UNIVERSAL HLTH SVCS INCCL B9139031005353,989SH SOLE 000
VBI VACCINES INCCOM91790E10212,0803,058,433SH SOLE 000
VCA INCCOM9181941015377,940SH SOLE 000
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VERSARTIS INCCOM92529L10231,3632,835,754SH SOLE 000
VERTEX PHARMACEUTICALS INCCOM92532F10011,183130,000SH SOLE 000
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VWR CORPCOM91843L10353918,657SH SOLE 000
WAVE LIFE SCIENCES LTDSHSY9530810510,812522,595SH SOLE 000
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