The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number:3235-0006
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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ANI PHARMACEUTICALS INCCOM00182C10320,300327,157SH SOLE 000
ANI PHARMACEUTICALS INCNOTE 3.000%12/000182CAA18,4887,500,000PRN SOLE 000
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ABEONA THERAPEUTICS INC*W EXP 12/19/20100289Y1152,2501,250,000SH SOLE 000
ABIOMED INCCOM365410065710,000SH SOLE 000
ACADIA PHARMACEUTICALS INCCOM422510817,181410,240SH SOLE 000
ACASTI PHARMA INCCL A SHS00430K1057452,365,600SH SOLE 000
ACCELERON PHARMA INCCOM00434H1088,734276,036SH SOLE 000
ACHAOGEN INCCOM444910436260,000SH SOLE 000
ACELRX PHARMACEUTICALS INCCOM00444T10027,8746,574,060SH SOLE 000
AETNA INC NEWCOM00817Y1081,28610,086SH SOLE 000
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APPLIED GENETIC TECHNOL CORPCOM03820J1004,616300,922SH SOLE 000
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ARDELYX INCCOM396971075,046315,955SH SOLE 000
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ASCENDIS PHARMA A SSPONSORED ADR04351P10117610,000SH SOLE 000
ASSEMBLY BIOSCIENCES INCCOM4539610815,117784,893SH SOLE 000
AVINGER INCCOM537341091,323102,500SH SOLE 000
BELLICUM PHARMACEUTICALSCOM7948110711,754552,628SH SOLE 000
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CELYAD SAADR1512052003,90275,000SH SOLE 000
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CHINA BIOLOGIC PRODS INCCOM16938C10616,998147,604SH SOLE 000
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COGENTIX MED INCCOM19243A1041,091673,257SH SOLE 000
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COMMUNITY HEALTH SYS INC NEWCOM2036681082503,978SH SOLE 000
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CONMED CORPCOM2074101014988,554SH SOLE 000
CORBUS PHARMACEUTICALS HOLDINGS INCCOM21833P1032,679870,000SH SOLE 000
CREDIT SUISSE NASSAU BRHINVRS VIX STERM22542D7951624,000SH SOLE 000
DBV TECHNOLOGIES S ASPONSORED ADR23306J101893,002SH SOLE 000
DANAHER CORP DELCOM23585110285610,000SH SOLE 000
DERMA SCIENCES INCCOM PAR $.0124982750224,997348,784SH SOLE 000
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DYAX CORPCOM26746E10347,3371,786,315SH SOLE 000
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INC RESH HLDGS INCCL A45329R1092917,261SH SOLE 000
INCYTE CORPCOM45337C1021,56315,000SH SOLE 000
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INTERSECT ENT INCCOM46071F10329310,251SH SOLE 000
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IRONWOOD PHARMACEUTICALS INCCOM CL A46333X1085,953493,600SH SOLE 000
ISHARES TRHDG MSCI GERMN46434V7042,27087,000SH SOLE 000
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KERYX BIOPHARMACEUTICALS INCCOM49251510134334,380SH SOLE 000
LHC GROUP INCCOM50187A1072265,917SH SOLE 000
LA JOLLA PHARMACEUTICAL COCOM PAR $.0001 25034596046,199252,915SH SOLE 000
LEMAITRE VASCULAR INCCOM52555820123919,838SH SOLE 000
LION BIOTECHNOLOGIES INCCOM53619R10225,3052,759,593SH SOLE 000
MGC DIAGNOSTICS CORPCOM5527681031,762336,287SH SOLE 000
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MAGELLAN HEALTH INCCOM NEW5590792072032,900SH SOLE 000
MCKESSON CORPCOM58155Q1032281,015SH SOLE 000
MEDGENICS INCCOM NEW58436Q2032,852465,225SH SOLE 000
MERGE HEALTHCARE INCCOM58949910226455,015SH SOLE 000
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MOLINA HEALTHCARE INCCOM60855R1002032,888SH SOLE 000
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NEPTUNE TECHNOLOGIES BIORESOCOM64077P1088,6436,700,444SH SOLE 000
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NEVRO CORPCOM64157F10342,944798,959SH SOLE 000
NOVO-NORDISK A SADR6701002051282,340SH SOLE 000
ONCOTHYREON INCCOM68232410812,5173,346,897SH SOLE 000
OREXIGEN THERAPEUTICS INCCOM68616410435070,600SH SOLE 000
OTONOMY INCCOM68906L1058,446367,386SH SOLE 000
PACIRA PHARMACEUTICALS INCCOM695127100450SH SOLE 000
PFENEX INCCOM71707110419,6111,010,877SH SOLE 000
PHARMERICA CORPCOM71714F1042266,800SH SOLE 000
PHIBRO ANIMAL HEALTH CORPCL A COM71742Q1062656,809SH SOLE 000
PORTOLA PHARMACEUTICALS INCCOM7370101085,061111,103SH SOLE 000
POWERSHS DB US DOLLAR INDEXDOLL INDX BULL73936D1072,25390,000SH SOLE 000
PROSHARES TRPSHS ULT S&P 50074347R1071,93630,000SH SOLE 000
PROSHARES ULTRA S & P500PSHS ULT S&P 50074347R1073,22750,000SHPutSOLE 000
PROTEON THERAPEUTICS INCCOM74371L1094,912275,000SH SOLE 000
PSIVIDA CORPCOM74440J1011,187315,000SH SOLE 000
PUMA BIOTECHNOLOGY INCCOM74587V10711,675100,000SHCallSOLE 000
RADIUS HEALTH INCCOM NEW75046920715,945235,530SH SOLE 000
RAPTOR PHARMACEUTICAL CORPCOM75382F1064,172264,204SH SOLE 000
RECEPTOS INCCOM75620710611,58760,969SH SOLE 000
REGULUS THERAPEUTICS INCCOM75915K1012,196200,000SHPutSOLE 000
RELYPSA INCCOM75953110637,6941,139,142SH SOLE 000
RETROPHIN INCCOM7612991063,315100,000SHPutSOLE 000
RETROPHIN INCCOM76129910691,6502,820,875SH SOLE 000
STREETTRACKS SPDR BIOTEC ETFS&P BIOTECH78464A87037,836150,000SHPutSOLE 000
SAGE THERAPEUTICS INCCOM78667J1081,46020,000SH SOLE 000
SANGAMO BIOSCIENCES INCCOM8006771068,872800,000SH SOLE 000
Sarepta Therapeutics IncCOM80360710015,215500,000SHCallSOLE 000
SAREPTA THERAPEUTICS INCCOM80360710085,4942,809,528SH SOLE 000
SCYNEXIS INCCOM8112921011,538175,000SH SOLE 000
SERES THERAPEUTICS INCCOM81750R1022,07550,000SH SOLE 000
SHIRE PLCSPONSORED ADR82481R1069,66040,000SH SOLE 000
STEMLINE THERAPEUTICS INCCOM85858C10793379,245SH SOLE 000
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SUPERNUS PHARMACEUTICALS INCNOTE 7.500% 5/0868459AB47,0082,187,000PRN SOLE 000
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TESARO INCCOM88156910749,111835,359SH SOLE 000
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TOKAI PHARMACEUTICALS INCCOM88907J1076,455485,338SH SOLE 000
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TRANSENTERIX INCCOM NEW89366M2016,1322,044,032SH SOLE 000
TRILLIUM THERAPEUTICS INCCOM NEW89620X50665530,000SH SOLE 000
TRIPLE-S MGMT CORPCL B89674910827210,605SH SOLE 000
UNITEDHEALTH GROUP INCCOM91324P1022061,685SH SOLE 000
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