The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number:3235-0006
Expires:Oct 31, 2018
Estimated average burden
hours per response:23.8

COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ACADIA PHARMACEUTICALS INCCOM00422510814,751653,000SH SOLE 653,00000
ACASTI PHARMA INCCL A SHS00430K1052,4372,566,785SH SOLE 2,566,78500
ACCELERON PHARMA INCCOM00434H10810,191300,000SH SOLE 300,00000
ACHAOGEN INCCOM00444910483860,000SH SOLE 60,00000
ACELRX PHARMACEUTICALS INCCOM00444T10067,3846,574,060SH SOLE 6,574,06000
ACHILLION PHARMACEUTICALS INCOM00448Q2012,120280,000SH SOLE 280,00000
AEGERION PHARMACEUTICALS ORDCOM00767E1023,209100,000SHCallSOLE 100,00000
AETNA INC NEWCOM00817Y10810,646131,308SH SOLE 131,30800
ALLERGAN INCCOM0184901028,46150,000SH SOLE 50,00000
ALMOST FAMILY INCCOM0204091081044,708SH SOLE 4,70800
ALLIQUACOM00771V1084,1961,121,951SH SOLE 1,121,95100
AMICUS THERAPEUTICS INCCOM03152W10941,21412,339,444SH SOLE 12,339,44400
AMSURG CORPCOM03232P405901,980SH SOLE 1,98000
ANACOR PHARMACEUTICALS INCCOM0324201019,375528,776SH SOLE 528,77600
ANTHERA PHARMACEUTICALS INCCOM NEW3674U2011,622478,456SH SOLE 478,45600
APPLIED GENETIC TECHNOL CORPCOM03820J1003,395146,978SH SOLE 146,97800
AQUINOX PHARMACEUTICALS INCCOM03842B1011,218130,000SH SOLE 130,00000
ARENA PHARMACEUTICALS INCCOM04004710217630,000SHPutSOLE 30,00000
ARNO THERAPEUTICSCOM425642033,6212,034,721SH SOLE 2,034,72100
ARROWHEAD RESH CORPCOM NEW0427972096,045422,406SH SOLE 422,40600
ATHERSYS INCCOM04744L1061,077601,852SH SOLE 601,85200
BARD C R INCCOM06738310997676SH SOLE 67600
BIODELIVERY SCIENCES INTL INCOM09060J1068,449700,000SH SOLE 700,00000
BIOTA PHARMACEUTIALS INCCOM090694100722253,400SH SOLE 253,40000
BIOLINERX LTDSPONSORED ADR09071M106345165,698SH SOLE 165,69800
BIOSPECIFICS TECHNOLOGIES COCOM0909311061003,700SH SOLE 3,70000
CATALYST PHARM PARTNERS INCCOM14888U1013,7951,500,000SH SOLE 1,500,00000
CELGENE CORPCOM15102010443,580507,488SH SOLE 507,48800
CENTENE CORP DELCOM15135B1014,53760,000SH SOLE 60,00000
CHAMPIONS ONCOLOGYCOM15870p1091,6251,625,744SH SOLE 1,625,74400
CHARLES RIV LABS INTL INCCOM1598641071001,860SH SOLE 1,86000
CHIMERIX INCCOM16934W1063,241148,000SH SOLE 148,00000
CHINA BIOLOGIC PRODS INCCOM16938C1061072,400SH SOLE 2,40000
CLOVIS ONCOLOGY INCCOM18946410045210,917SH SOLE 10,91700
DERMA SCIENCES INCCOM PAR $.012498275024,698406,437SH SOLE 406,43700
DURECT CORPCOM2666051041,651907,064SH SOLE 907,06400
DYAX CORPCOM26746E10326,0222,710,598SH SOLE 2,710,59800
ENSIGN GROUP INCCOM29358P1011093,509SH SOLE 3,50900
EPIZYME INCCOM29428V1041,32642,602SH SOLE 42,60200
EXACT SCIENCES CORPCOM30063P10515,348901,250SH SOLE 901,25000
EXACTECH INCCOM30064E1091134,464SH SOLE 4,46400
EXELIXIS INCCOM30161Q1041,356400,000SHCallSOLE 400,00000
FIVE PRIME THERAPEUTICS INCCOM33830X1042,333150,000SH SOLE 150,00000
FLAMEL TECHNOLOGIES SASPONSORED ADR33848810912,000800,000SH SOLE 800,00000
GENVEC INCCOM NEW37246C3072,107820,000SH SOLE 820,00000
GENTIVA HEALTH SERVICES INCCOM37247A1021067,052SH SOLE 7,05200
HCA HOLDINGS INCCOM40412C10111,152197,806SH SOLE 197,80600
HEALTH NET INCCOM42222G1082506,025SH SOLE 6,02500
HERON THERAPEUTICS INCCOM42774610217,7381,439,770SH SOLE 1,439,77000
HERON THERAPEUTICS INCCOM4277461022,400194,785SH SOLE 194,78500
HUMANA INCCOM444859102103803SH SOLE 80300
ICAD INCCOM NEW44934S206962150,000SH SOLE 150,00000
INCYTE CORPCOM45337C1021,12920,000SH SOLE 20,00000
INSMED INCCOM PAR $.0145766930735,9641,800,000SH SOLE 1,800,00000
INTERCEPT INCCOM45845P1084,73320,000SHPutSOLE 20,00000
INTERMUNE INCCOM45884X1039,272210,000SH SOLE 210,00000
KARYOPHARM THERAPEUTICS INCCOM48576U1062,12545,643SH SOLE 45,64300
LIGAND PHARMACEUTICALS INCCOM NEW53220K5041,73427,843SH SOLE 27,84300
LION BIOTECHNOLOGIESCOM53619R10219,2733,011,549SH SOLE 3,011,54900
MGC DIAGNOSTICS CORPCOM5527681032,652316,459SH SOLE 316,45900
MACROGENICS INCCOM5560991099,383431,803SH SOLE 431,80300
MAGELLAN HEALTH INCCOM NEW5590792071021,642SH SOLE 1,64200
MCKESSON CORPCOM58155Q10399530SH SOLE 53000
MEDASSETS INCCOM5840451081014,429SH SOLE 4,42900
MEDGENICS INCCOM NEW58436Q20342855,073SH SOLE 55,07300
MEDTRONIC INCCOM5850551068,289130,000SH SOLE 130,00000
MERGE HEALTHCARE INCCOM5894991029943,478SH SOLE 43,47800
MOLINA HEALTHCARE INCCOM60855R1001062,380SH SOLE 2,38000
MYLAN INCCOM62853010714,566282,500SH SOLE 282,50000
NEPTUNE TECHNOLOGIES BIORESOCOM64077P10818,4936,700,444SH SOLE 6,700,44400
NEUROCRINE BIOSCIENCES INCCOM64125C10968,2624,599,867SH SOLE 4,599,86700
NEWLINK GENETICS CORPCOM6515111071,32850,000SHCallSOLE 50,00000
ONCOTHYREON INCCOM682324108949292,779SH SOLE 292,77900
OPHTHOTECH CORPCOM68374510315,717371,469SH SOLE 371,46900
OREXIGEN THERAPEUTICS INCCOM6861641041,384224,000SH SOLE 224,00000
OXIGENE INCCOM PAR$.001691828404982379,200SH SOLE 379,20000
PDL BIOPHARMA INCCOM69329Y1049910,183SH SOLE 10,18300
PTC THERAPEUTICS INCCOM69366J20017,559671,736SH SOLE 671,73600
PHARMERICA CORPCOM71714F104983,441SH SOLE 3,44100
QUESTCOR PHARMACEUTICALS INCCOM74835Y10136,996400,000SH SOLE 400,00000
QUINTILES TRANSNATIO HLDGS ICOM74876Y1011001,875SH SOLE 1,87500
RADNET INCCOM75049110215222,975SH SOLE 22,97500
RECEPTOS INCCOM7562071068,733205,000SH SOLE 205,00000
REGADO BIOSCIENCES INCCOM75874Q1075,839860,000SH SOLE 860,00000
RELYPSA INCCOM75953110614,509596,605SH SOLE 596,60500
RETROPHIN INCCOM76129910614,9601,274,292SH SOLE 1,274,29200
SANGAMO BIOSCIENCES INCCOM80067710612,216800,000SH SOLE 800,00000
SAREPTA THERAPEUTICS INCCOM80360710076,2172,558,478SH SOLE 2,558,47800
SHIRE PLCSPONSORED ADR82481R10621,19490,000SH SOLE 90,00000
SMITH & NEPHEW PLCSPDN ADR NEW83175M2052,05022,963SH SOLE 22,96300
SPECTRANETICS CORPCOM84760C1075,568243,354SH SOLE 243,35400
STEMCELLS INCCOM NEW85857R204551271,600SH SOLE 271,60000
SUNSHINE HEART INCCOM86782U10614025,000SH SOLE 25,00000
SYMMETRY MED INCCOM8715462069911,148SH SOLE 11,14800
TESARO INCCOM88156910719,816636,956SH SOLE 636,95600
TESARO INCCOM8815691073,111100,000SHPutSOLE 100,00000
TRANSGENOMIC INCCOM NEW89365K305687183,957SH SOLE 183,95700
TRANSENTERIX INCCOM NEW89366M2016,5521,300,000SH SOLE 1,300,00000
TREVENA INCCOM89532E1094,351770,000SH SOLE 770,00000
TRIPLE-S MGMT CORPCL B8967491081055,880SH SOLE 5,88000
UNIVERSAL HLTH SVCS INCCL B9139031002142,236SH SOLE 2,23600
UROPLASTY INCCOM NEW9172772041,791668,287SH SOLE 668,28700
VERSARTIS INCCOM92529L1028,855315,796SH SOLE 315,79600
VERTEX PHARMACEUTICALS INCCOM92532F1002,84030,000SHPutSOLE 30,00000
VERTEX PHARMACEUTICALS INCCOM92532F10044,513470,142SH SOLE 470,14200
WALGREEN COCOM9314221093,70750,000SHCallSOLE 50,00000
WALGREEN COCOM93142210920,905282,000SH SOLE 282,00000
WELLCARE HEALTH PLANS INCCOM94946T106971,302SH SOLE 1,30200
XENCOR INCCOM98401F10520,2261,740,621SH SOLE 1,740,62100
ZELTIQ AESTHETICS INCCOM98933Q1083,065201,628SH SOLE 201,62800
ZIMMER HLDGS INCCOM98956P10225,186242,500SH SOLE 242,50000
COVIDIEN PLCSHSG2554F1132,25525,000SH SOLE 25,00000
ICON PLCSHSG4705A1001152,440SH SOLE 2,44000
PROTHENA CORP PLCSHSG7280010810,895483,162SH SOLE 483,16200
QUOTIENT LTDSHSG732681072,499300,000SH SOLE 300,00000
GALMED PHARMACEUTICALS LTDSHSM4723810673175,000SH SOLE 75,00000
SYNERON MEDICAL LTDORD SHSM872451021,187115,000SH SOLE 115,00000
TARO PHARMACEUTICAL INDS LTDSHSM8737E108130924SH SOLE 92400
TARO PHARMACEUTICAL INDS LTDSHSM8737E10819,560139,474SH SOLE 139,47400
TARO PHARMACEUTICAL INDS LTDSHSM8737E10822,570160,935SH SOLE 160,93500