The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number:3235-0006
Expires:Oct 31, 2018
Estimated average burden
hours per response:23.8

COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ACASTI PHARMA INCCL A SHS00430K1055,2364,389,685SH SOLE 4,389,68500
AERIE PHARMACEUTICALS INCCOM00771V1085,388300,000SH SOLE 300,00000
AXOGEN INCCOM05463X106204,500SH SOLE 4,50000
BLUEBIRD BIO INCCOM09609G10042020,000SH SOLE 20,00000
CHIMERIX INCCOM16934W1062,262150,000SH SOLE 150,00000
FIVE PRIME THERAPEUTICS INCCOM33830X1042,225132,500SH SOLE 132,50000
GENTIUM S P ASPONSORED ADR37250B1046,852120,000SH SOLE 120,00000
MACROGENICS INCCOM55609910919,687717,705SH SOLE 717,70500
MGC DIAGNOSTICS CORPCOM5527681032,274179,619SH SOLE 179,61900
OREXIGEN THERAPEUTICS INCNOTE 2.750%12/0686164AA2732750,000PRN SOLE 750,00000
RELYPSA INCCOM7595311068,530341,200SH SOLE 341,20000
STEMCELLS INCCOM NEW85857R204334271,600SH SOLE 271,60000
STEMLINE THERAPEUTICS INCCOM85858C107138SH SOLE 3800
SURGICAL CARE AFFILIATES INCCOM86881L10669720,000SH SOLE 20,00000
TANDEM DIABETES CARE INCCOM8753721042,995116,235SH SOLE 116,23500
VERASTEM INCCOM92337C1042,517220,000SH SOLE 220,00000
XENCOR INCCOM98401F10514,3381,568,672SH SOLE 1,568,67200
ABBVIE INCCOM00287Y10918,484350,000SH SOLE 350,00000
ACELRX PHARMACEUTICALS INCCOM00444T10074,3536,574,060SH SOLE 6,574,06000
AEGERION PHARMACEUTICALS INCCOM00767E10231,775447,785SH SOLE 447,78500
AFFYMETRIX INCCOM00826T108738,538SH SOLE 8,53800
ALERE INCCOM01449J1051494,127SH SOLE 4,12700
ALLIQUACOM0196212004,041557,491SH SOLE 557,49100
ANACOR PHARMACEUTICALS INCCOM324201017,959474,303SH SOLE 474,30300
ANACOR PHARMACEUTICALS INCCOM3242010122213,239SH SOLE 13,23900
ANALOGIC CORPCOM PAR $0.05326572071461,644SH SOLE 1,64400
ANTHERA PHARMACEUTICALS INCCOM NEW03674U2011,325431,456SH SOLE 431,45600
ARNO THERAPEUTICSCOM0425642035,6972,034,721SH SOLE 2,034,72100
ASTRAZENECA PLCSPONSORED ADR463531081522,558SH SOLE 2,55800
ATHENAHEALTH INCCOM04685W1033362,500SHCallSOLE 2,50000
ATHERSYS INCCOM04744L1064,2521,700,887SH SOLE 1,700,88700
AUXILIUM PHARMACEUTICALS INCCOM05334D1072,074100,000SH SOLE 100,00000
BIOCRYST PHARMACEUTICALSCOM09058V1031,501197,500SH SOLE 197,50000
BIOGEN IDEC INCCOM09062X10311,19040,000SH SOLE 40,00000
CAPITAL SR LIVING CORPCOM1404751045,008208,753SH SOLE 208,75300
CELGENE CORPCOM15102010486,034509,200SH SOLE 509,20000
CELL THERAPEUTICS INCCOM NPV NEW 20121509348837,1333,715,000SH SOLE 3,715,00000
CENTENE CORP DELCOM15135B1011542,610SH SOLE 2,61000
CHAMPION ONCOLOGYCOM15870P1091,9501,625,744SH SOLE 1,625,74400
CHELSEA THERAPEUTICS INTL LTCOM1634281057,5381,701,639SH SOLE 1,701,63900
CIGNA CORPORATIONCOM12550910910,935125,000SH SOLE 125,00000
CLOVIS ONCOLOGY INCCOM1894641001,84330,585SH SOLE 30,58500
COMBIMATRIX CORPORATION*W EXP 05/01/20120009T12135,000SH SOLE 5,00000
COVIDIEN PLCSHSG2554F11311,640170,926SH SOLE 170,92600
COVIDIEN PLCSHSG2554F1133755,500SH SOLE 5,50000
COVIDIEN PLCSHSG2554F11313,511198,400SH SOLE 198,40000
CURIS INCCOM231269101987350,000SH SOLE 350,00000
CUTERA INCCOM23210910822822,400SH SOLE 22,40000
CVS CAREMARK CORPORATIONCOM1266501006,24187,200SH SOLE 87,20000
CVS CAREMARK CORPORATIONCOM1266501001522,130SH SOLE 2,13000
DAVITA HEALTHCARE PARTNERS ICOM23918K1081512,382SH SOLE 2,38200
DEXCOM INCCOM2521311071,06230,000SH SOLE 30,00000
DYAX CORPCOM26746E10317,5652,332,674SH SOLE 2,332,67400
ENDO HEALTH SOLUTIONS INCCOM29264F205771,138SH SOLE 1,13800
ENDOCYTE INCCOM29269A1024,504421,300SH SOLE 421,30000
ENDOCYTE INCCOM29269A1022,138200,000SHPutSOLE 200,00000
ENDOCYTE INCCOM29269A1022,138200,000SHCallSOLE 200,00000
ENZO BIOCHEM INCCOM29269A102730250,000SH SOLE 250,00000
EXACT SCIENCES CORPCOM30063P10522,4801,923,003SH SOLE 1,923,00300
EXACT SCIENCES CORPCOM30063P10555146,900SH SOLE 46,90000
EXPRESS SCRIPTS HLDG COCOM30219G1081462,080SH SOLE 2,08000
FLUIDIGM CORP DELCOM34385P108782,030SH SOLE 2,03000
GERON CORPCOM374163103224,684SH SOLE 4,68400
GILEAD SCIENCES INCCOM3755581033,75850,000SH SOLE 50,00000
HEALTH NET INCCOM42222G1087,937267,500SH SOLE 267,50000
HEALTH NET INCCOM42222G1081575,275SH SOLE 5,27500
HEARTWARE INTL INCCOM4223681007,97784,900SH SOLE 84,90000
HILL ROM HLDGS INCCOM4314751021523,687SH SOLE 3,68700
HOLOGIC INCCOM43644010155925,000SHCallSOLE 25,00000
IDENIX PHARMACEUTICALS INCCOM45166R2041,794300,000SHCallSOLE 300,00000
ILLUMINA INCCOM4523271092212,000SH SOLE 2,00000
IMMUNOMEDICS INCCOM452907108132,853SH SOLE 2,85300
IMPAX LABORATORIES INCCOM45256B1011505,962SH SOLE 5,96200
INCYTE CORPCOM45337C10213,609268,800SH SOLE 268,80000
INFINITY PHARMACEUTICALS INCCOM45665G3034,834350,000SH SOLE 350,00000
INSYS THERAPEUTICS INC NEWCOM NEW45824V2092215,722SH SOLE 5,72200
LANNET INCCOM5160121012236,744SH SOLE 6,74400
MANNKIND CORPCOM56400P20119,7723,795,000SH SOLE 3,795,00000
MEDGENICS INCCOM NEW58436Q20336761,263SH SOLE 61,26300
MEDIDATA SOLUTIONS INCCOM58471A1052203,642SH SOLE 3,64200
MIMEDX GROUP INCCOM602496101874100,000SH SOLE 100,00000
MYLAN INCCOM62853010717,035392,500SH SOLE 392,50000
MYRIAD GENETICS INCCOM62855J10421010,000SHPutSOLE 10,00000
NANOSPHERE INCCOM63009F105676295,000SH SOLE 295,00000
NAVIDEA BIOPHARMACEUTICALS ICOM63937X103207100,000SHPutSOLE 100,00000
NEOSTEM INCCOM PAR $.0016406504041,566229,593SH SOLE 229,59300
NEPTUNE TECHNOLOGIES BIORESOCOM64077P10817,1115,900,444SH SOLE 5,900,44400
NEUROCRINE BIOSCIENCES INCCOM64125C10939,0764,183,737SH SOLE 4,183,73700
NEWCASTLE INVT CORPCOM65105M10840270,000SH SOLE 70,00000
OMNICARE INCCOM6819041081502,492SH SOLE 2,49200
ONCOTHYREON INCCOM682324108880500,000SH SOLE 500,00000
OPHTHOTECH CORPCOM6837451032,42675,000SH SOLE 75,00000
PAIN THERAPEUTICS INCCOM69562K10017235,506SH SOLE 35,50600
PUMA BIOTECHNOLOGY INCCOM74587V10776735SH SOLE 73500
REPLIGEN CORPCOM7599161092,251165,000SHPutSOLE 165,00000
REPROS THERAPEUTICS INCCOM NEW76028H2091,31571,879SH SOLE 71,87900
RETROPHIN INCCOM7612991067,3681,052,692SH SOLE 1,052,69200
RITE AID CORPCOM7677541047614,924SH SOLE 14,92400
SANTARUS INCCOM8028173041,45145,400SH SOLE 45,40000
SAREPTA THERAPEUTICS INCCOM80360710070,9813,484,579SH SOLE 3,484,57900
Sarepta Therapeutics IncCOM80360710013,241650,000SHPutSOLE 650,00000
SHIRE PLCSPONSORED ADR82481R1061,41310,000SH SOLE 10,00000
SPECTRANETICS CORPCOM84760C1078,656346,254SH SOLE 346,25400
TANDEM DIABETES CARE INCCOM8753721042419,365SH SOLE 9,36500
TARO PHARMACEUTICAL INDS LTDSHSM8737E1085,59856,602SH SOLE 56,60200
TESARO INCCOM88156910740,8511,446,570SH SOLE 1,446,57000
TORNIER N VSHSN8723710818810,000SH SOLE 10,00000
TRANSGENOMIC INCCOM89365k2061,0042,207,500SH SOLE 2,207,50000
UNITED THERAPEUTICS CORP DELCOM91307C1027927,000SH SOLE 7,00000
UROPLASTY INCCOM NEW917277204857313,989SH SOLE 313,98900
VERTEX PHARMACEUTICALS INCCOM92532F10060,311811,728SH SOLE 811,72800
VIVUS INCCOM928551100908100,000SHPutSOLE 100,00000
WALGREEN COCOM93142210918,496322,000SH SOLE 322,00000
XENOPORT INCCOM98411C10028850,000SH SOLE 50,00000
ZELTIQ AESTHETICS INCCOM98933Q1085,548293,400SH SOLE 293,40000
ZELTIQ AESTHETICS INCCOM98933Q10823112,193SH SOLE 12,19300
ZIMMER HLDGS INCCOM98956P1021,86420,000SH SOLE 20,00000
ZOGENIX INCCOM98978L1052,236650,000SH SOLE 650,00000