The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
1LIFE HEALTHCARE INCCOM68269G1077,948218,844SH SOLE 218,84400
ADAPTIMMUNE THERAPEUTICS PLCSPONDS ADR00653A1074,004400,000SH SOLE 400,00000
ADAPTIVE BIOTECHNOLOGIES CORCOM00650F10923,222480,000SH SOLE 480,00000
ADMA BIOLOGICS INCCOM00089910448,59316,584,802SH SOLE 16,584,80200
AGILE THERAPEUTICS INCCOM00847L10044,25715,919,925SH SOLE 15,919,92500
AGIO PHARMACEUTICALS INCCOM00847X10448,132900,000SH SOLE 900,00000
AKEBIA THERAPEUTICS INCCOM00972D10571652,724SH SOLE 52,72400
ALBIREO PHARMA INCCOM01345P10651,9241,960,139SH SOLE 1,960,13900
ALDEYRA THERAPEUTICS INCCOM01438T10612,8663,085,458SH SOLE 3,085,45800
ALECTOR INCCOM01444210712,507511,731SH SOLE 511,73100
ALLOGENE THERAPEUTICS INCCOM01977010666,1051,543,790SH SOLE 1,543,79000
ALPHATEC HLDGS INCCOM NEW02081G2012,639561,574SH SOLE 561,57400
AMICUS THERAPEUTICS INCCOM03152W109379,75025,182,364SH SOLE 25,182,36400
AMYRIS INCCOM NEW03236M2006,4491,844,612SH SOLE 1,844,61200
APELLIS PHARMACEUTICALS INCCOM03753U10637311,418SH SOLE 11,41800
AQUESTIVE THERAPEUTICS INCCOM03843E1048,5051,750,000SH SOLE 1,750,00000
ARENA PHARMACEUTICALS INCCOM NEW04004760768,9381,095,129SH SOLE 1,095,12900
ATHENEX INCCOM04685N103155,93511,532,467SH SOLE 11,532,46700
ATRICURE INCCOM04963C20923,768528,776SH SOLE 528,77600
AVADEL PHARMACEUTICALS PLCSPONSORED ADR05337M1041338,681SH SOLE 8,68100
AVIDITY BIOSCIENCES INCCOM05370A10831,6131,235,818SH SOLE 1,235,81800
AXSOME THERAPEUTICS INCCOM05464T1044,11450,000SH SOLE 50,00000
BELLUS HEALTH INC NEWCOM NEW07987C20411,5761,125,000SH SOLE 1,125,00000
BIO RAD LABS INCCL A0905722076,99315,489SH SOLE 15,48900
BLACK DIAMOND THERAPEUTICS ICOM09203E10543,9961,104,656SH SOLE 1,104,65600
BLUEPRINT MEDICINES CORPCOM09627Y10953,713688,624SH SOLE 688,62400
BRIDGEBIO PHARMA INCCOM10806X102218,6916,706,268SH SOLE 6,706,26800
BURNING ROCK BIOTECH LTDSPONSORED ADS12233L1074,052150,000SH SOLE 150,00000
CHEMOCENTRYX INCCOM16383L10659010,252SH SOLE 10,25200
COHERUS BIOSCIENCES INCCOM19249H1039,739545,285SH SOLE 545,28500
COLLEGIUM PHARMACEUTICAL INCCOM19459J10436,0162,058,068SH SOLE 2,058,06800
COLLEGIUM PHARMACEUTICAL INCNOTE 2.625% 2/119459JAA2157,22717,500,000PRN SOLE 17,500,00000
CONCERT PHARMACEUTICALS INCCOM20602210521,3982,150,641SH SOLE 2,150,64100
CRINETICS PHARMACEUTICALS INCOM22663K10759,1713,659,381SH SOLE 3,659,38100
CUE BIOPHARMA INCCOM22978P10664626,371SH SOLE 26,37100
CYTOKINETICS INCNOTE 4.000%11/123282WAA8238,26010,000,000PRN SOLE 10,000,00000
CYTOMX THERAPEUTICS INCCOM23284F10521,4672,577,043SH SOLE 2,577,04300
DBV TECHNOLOGIES S ASPONSORED ADR23306J10132,1257,317,809SH SOLE 7,317,80900
DENALI THERAPEUTICS INC COM28423R10520,553850,000SH SOLE 850,00000
DERMTECH INCCOM24984K1056,445487,121SH SOLE 487,12100
DICERNA PHARMACEUTICALS INCCOM25303110820,320800,000SH SOLE 800,00000
DYNAVAX TECHNOLOGIES CORPCOM NEW2681582011,570176,950SH SOLE 176,95000
EIDOS THERAPEUTICS INCCOM28249H10430,115686,922SH SOLE 686,92200
EIGER BIOPHARMACEUTICALS INCCOM28249U1051,343139,890SH SOLE 139,89000
ESTABLISHMENT LABS HOLDINGS INCSHSG3124910813,750736,121SH SOLE 736,12100
FORMA THERAPEUTICS HLDGS INCSHS34633R10458,1131,250,000SH SOLE 1,250,00000
FERRARI N.VSHSN3167Y1031,0606,200SH SOLE 6,20000
FREQUENCY THERAPEUTICS INCCOM35803L10870,5473,034,296SH SOLE 3,034,29600
FULCRUM THERAPEUTICS INCCOM35961610915,768894,118SH SOLE 894,11800
FUSION PHARMACEUTICALS INCCOM36118A10035,9552,235,983SH SOLE 2,235,98300
GALERA THERAPEUTICS INCCOM36338D1082,321325,000SH SOLE 325,00000
GERON CORPCOM37416310329,34613,461,538SH SOLE 13,461,53800
GLOBAL BLOOD THERAPEUTICS INCOM37890U108368,8115,842,100SH SOLE 5,842,10000
HEALTH CATALYST INCCOM42225T1079,795335,782SH SOLE 335,78200
HOLOGIC INCCOM43644010113,110230,000SH SOLE 230,00000
IMMUNOMEDICS INCCOM45290710812,834362,140SH SOLE 362,14000
IMMUNOMEDICS INCCOM4529071083,544100,000SHPutSOLE 100,00000
IMMUNOVANT INCCOM45258J10226,7851,100,000SH SOLE 1,100,00000
INARI MED INCCOM45332Y10933,714696,000SH SOLE 696,00000
INSULET CORPCOM45784P10110,24452,733SH SOLE 52,73300
IOVANCE BIOTHERAPEUTICS INCCOM462260100324,17011,809,494SH SOLE 11,809,49400
IVERIC BIO INCCOM46583P10217,7553,481,431SH SOLE 3,481,43100
KADMON HLDGS INCCOM48283N10680,44215,711,334SH SOLE 15,711,33400
KARUNA THERAPEUTICS INCCOM48576A1007746,944SH SOLE 6,94400
KODIAK SCIENCES INCCOM50015M109190,1543,513,572SH SOLE 3,513,57200
LEAP THERAPEUTICS INCCOM52187K10117,4668,476,496SH SOLE 8,476,49600
LEGEND BIOTECH CORPSPONSORED ADS52490G1021,06425,000SH SOLE 25,00000
LIFESCI ACQUISITION CORPUNIT 03/31/202553228P2083,300300,000SH SOLE 300,00000
LIVONGO HEALTH INCCOM5391831031,02413,620SH SOLE 13,62000
LONGVIEW ACQUISITION CORPUNIT 99/99/99995431952007,070700,000SH SOLE 700,00000
LUMINEX CORP DELCOM55027E10261618,926SH SOLE 18,92600
LYRA THERAPEUTICS INCCOM55234L10536,5433,222,561SH SOLE 3,222,56100
MACROGENICS INCCOM55609910935,9611,288,014SH SOLE 1,288,01400
MEDTRONIC PLCSHSG5960L1031,83420,000SH SOLE 20,00000
MEIRAGTX HOLDINGS PLCCOMG5966510280,5446,433,277SH SOLE 6,433,27700
MENLO THERAPEUTICS INCCOM58685810239,57622,876,410SH SOLE 22,876,41000
MIRATI THERAPEUTICS INCCOM60468T105316,3712,771,050SH SOLE 2,771,05000
MODERNA INCCOM60770K1076,421100,000SHPutSOLE 100,00000
MOLECULAR TEMPLATES INCCOM60855010934,1182,474,133SH SOLE 2,474,13300
MOMENTA PHARMACEUTICALS INCCOM60877T1001,01930,637SH SOLE 30,63700
MORPHIC HLDG INCCOM61775R10517,583650,000SH SOLE 650,00000
MOTUS GI HLDGS INCCOM62014P1085,5574,210,542SH SOLE 4,210,54200
MYLAN N.VSHS EURON5946510916,1511,004,419SH SOLE 1,004,41900
MYOKARDIA INCCOM62857M105134,7871,395,017SH SOLE 1,395,01700
NEOLEUKIN THERAPEUTICS INCCOM64049K1048,921537,425SH SOLE 537,42500
NEPTUNE WELLNESS SOLUTIONS ICOM64079L10551,62318,436,906SH SOLE 18,436,90600
NEUROCRINE BIOSCIENCES INCCOM64125C109261,2522,141,410SH SOLE 2,141,41000
NEVRO CORPCOM64157F103107,520899,972SH SOLE 899,97200
NEVRO CORPNOTE 2.750% 4/064157FAC7121,5009,000,000PRN SOLE 9,000,00000
NOVAVAX INCCOM NEW67000240129,173350,000SH SOLE 350,00000
OUTLOOK THERAPEUTICS INC*W EXP 02/18/20269012T115108420,875SH SOLE 420,87500
PHREESIA INCCOM71944F1061,97970,000SH SOLE 70,00000
PROVENTION BIO INCCOM74374N10263,8584,525,711SH SOLE 4,525,71100
QUOTIENT LTDCOMG7326810798,33813,289,054SH SOLE 13,289,05400
REGENERON PHARMACEUTICALSCOM75886F1079,35415,000SH SOLE 15,00000
REPRO MED SYS INCCOM75991010267274,813SH SOLE 74,81300
RETROPHIN INCCOM76129910628,8713,240,112SH SOLE 3,240,11200
RETROPHIN INCNOTE 2.500% 9/1761299AB2349,97945,000,000PRN SOLE 45,000,00000
REVANCE THERAPEUTICS INCCOM7613301091,60865,839SH SOLE 65,83900
REVOLUTION MEDICINES INCCOM76155X10011,050350,000SH SOLE 350,00000
ROCKET PHARMACEUTICALS INCCOM77313F10645,8162,189,010SH SOLE 2,189,01000
SC HEALTH CORPUNIT 99/99/9999G7851630210,1101,000,000SH SOLE 1,000,00000
SIERRA ONCOLOGY INCCOM NEW82640U40480766,655SH SOLE 66,65500
SILK RD MED INCCOM82710M10016,132385,100SH SOLE 385,10000
SOLID BIOSCIENCES INCCOM83422E10519,7776,749,803SH SOLE 6,749,80300
SPRINGWORKS THERAPEUTICS INCCOM85205L107147,6033,514,358SH SOLE 3,514,35800
STOKE THERAPEUTICS INCCOM86150R10716,013671,978SH SOLE 671,97800
TG THERAPEUTICS INCCOM88322Q10858029,762SH SOLE 29,76200
TRANSLATE BIO INCCOM89374L1045,649315,237SH SOLE 315,23700
TRILLIUM THERAPEUTICS INCCOM NEW89620X506928114,674SH SOLE 114,67400
TURNING POINT THERAPEUTICS ICOM90041T10821,308329,890SH SOLE 329,89000
TWIST BIOSCIENCE CORPCOM90184D10012,356272,756SH SOLE 272,75600
UROVANT SCIENCES LTDCOMG9381B10823,2892,366,831SH SOLE 2,366,83100
VAPOTHERM INCCOM92210710754,8761,338,760SH SOLE 1,338,76000
VAXCYTE INCCOM92243G10826,869850,000SH SOLE 850,00000
VBI VACCINES INCCOM NEW91822J103170,63155,042,465SH SOLE 55,042,46500
VERRICA PHARMACEUTICALS INCCOM92511W10837,5493,410,412SH SOLE 3,410,41200
VERU INCCOM92536C1035,5111,650,000SH SOLE 1,650,00000
VIEWRAY INCCOM92672L1075,4922,451,748SH SOLE 2,451,74800
VIR BIOTECHNOLOGY INCCOM92764N10253413,024SH SOLE 13,02400
VOCERA COMMUNICATIONS INCCOM92857F1076,148290,000SH SOLE 290,00000
Y-MABS THERAPEUTICS INCCOM98424110915,352355,366SH SOLE 355,36600
ZENTALIS PHARMACEUTICALS INCCOM98943L10745,7831,050,003SH SOLE 1,050,00300
ZOGENIX INCCOM NEW98978L204132,5424,907,139SH SOLE 4,907,13900
ZYMEWORKS INCCOM98985W102129,1663,580,999SH SOLE 3,580,99900