SCHEDULE 13G/A 0001224962 XXXXXXXX LIVE 1 Common Stock, par value $0.01 per share 03/31/2025 0001130598 Traws Pharma, Inc. 68232V884 12 Penns Trail Newtown PA 18940 Rule 13d-1(c) Perceptive Advisors LLC DE 0 545197 0 545197 545197 N 9.99 IA Joseph Edelman X1 0 545197 0 545197 545197 N 9.99 IN Perceptive Life Sciences Master Fund, Ltd. E9 0 545197 0 545197 545197 N 9.99 CO Traws Pharma, Inc. 12 Penns Trail, Newtown, PA 18940 The names of the persons filing this report (collectively, the "Reporting Persons") with respect to shares of Common Stock, par value $0.01 per share (the "Common Stock") of Traws Pharma, Inc. (the "Issuer") are: (i) Perceptive Advisors LLC ("Perceptive Advisors") (ii) Joseph Edelman ("Mr. Edelman") (iii) Perceptive Life Sciences Master Fund, Ltd. (the "Master Fund") The address of the principal business office of each of the Reporting Persons is: 51 Astor Place, 10th Floor, New York, NY 10003 Perceptive Advisors is a Delaware limited liability company. Mr. Edelman is a United States citizen. The Master Fund is a Cayman Islands corporation. Y The information required by this item with respect to each Reporting Person is set forth in Rows 5 through 9 of the cover pages to this Schedule 13G. The ownership percentages reported are based on 5,334,015 shares of Common Stock outstanding as of April 28, 2025, as reported in the Issuer's Annual Report on Form 10-K/A filed with the Securities and Exchange Commission on April 30, 2025 and give effect to the exercise of the Warrants (as defined below). The Master Fund directly holds 421,781 shares of Common Stock and warrants to purchase 123,416 shares of Common Stock (the "Warrants"). The Warrants may not be exercised if the Reporting Persons would beneficially own more than 9.99% of the Issuer's outstanding shares of Common Stock after giving effect to such exercise. Perceptive Advisors serves as the investment manager to the Master Fund. Mr. Edelman is the managing member of Perceptive Advisors. Perceptive Advisors: 9.99% Mr. Edelman: 9.99% Master Fund: 9.99 Perceptive Advisors: 0 Mr. Edelman: 0 Master Fund: 0 Perceptive Advisors: 545,197 Mr. Edelman: 545,197 Master Fund: 545,197 Perceptive Advisors: 0 Mr. Edelman: 0 Master Fund: 0 Perceptive Advisors: 545,197 Mr. Edelman: 545,197 Master Fund: 545,197 Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Perceptive Advisors LLC /s/ Joseph Edelman 05/15/2025 Joseph Edelman /s/ Joseph Edelman 05/15/2025 Perceptive Life Sciences Master Fund, Ltd. /s/ Joseph Edelman 05/15/2025