SCHEDULE 13D/A 0000950170-25-021237 0001224962 XXXXXXXX LIVE 4 Class A Ordinary Shares, $0.0109 par value per share 03/21/2025 false 0000888721 896438504 Trinity Biotech plc

IDA Business Park Bray Co. Wicklow L2 A98 H5C8

Alexander Rakitin (646) 205-5340 Perceptive Advisers LLC 51 Astor Place, 10th Floor New York NY 10003 Louis Rambo, Proskauer Rose (202) 416-6800 1001 Pennsylvania Avenue, NW Suite 600 South Washington DC 20004 0001224962 N Perceptive Advisors LLC b AF Y DE 0 85800000 0 85800000 85800000 N 19.8 OO The amounts reported herein assume the exercise of warrants held by the Reporting Persons for an aggregate of 50,000,000 Ordinary Shares. The warrants may not be exercised if the Reporting Persons would beneficially own more than 9.99% of the Issuer's outstanding Ordinary Shares after giving effect to such exercise. 0001877081 N Perceptive Credit Advisors LLC b AF Y DE 0 85800000 0 85800000 85800000 N 19.8 OO The amounts reported herein assume the exercise of warrants held by the Reporting Persons for an aggregate of 50,000,000 Ordinary Shares. The warrants may not be exercised if the Reporting Persons would beneficially own more than 9.99% of the Issuer's outstanding Ordinary Shares after giving effect to such exercise. 0001164426 N Joseph Edelman b AF Y X1 0 85800000 0 85800000 85800000 N 19.8 IN The amounts reported herein assume the exercise of warrants held by the Reporting Persons for an aggregate of 50,000,000 Ordinary Shares. The warrants may not be exercised if the Reporting Persons would beneficially own more than 9.99% of the Issuer's outstanding Ordinary Shares after giving effect to such exercise. Y Perceptive Credit Holdings II, L.P. b WC Y DE 0 45800000 0 45800000 45800000 N 10.6 PN The amounts reported herein assume the exercise of warrants held by Perceptive Credit Holdings II, L.P. for an aggregate of 10,000,000 Ordinary Shares. The warrants may not be exercised if the Reporting Persons would beneficially own more than 9.99% of the Issuer's outstanding Ordinary Shares after giving effect to such exercise. 0001877078 N Perceptive Credit Holdings III, L.P. b WC Y DE 0 40000000 0 40000000 40000000 N 9.2 PN The amounts reported herein assume the exercise of warrants held by Perceptive Credit Holdings III, L.P. for an aggregate of 40,000,000 Ordinary Shares. The warrants may not be exercised if the Reporting Persons would beneficially own more than 9.99% of the Issuer's outstanding Ordinary Shares after giving effect to such exercise. Class A Ordinary Shares, $0.0109 par value per share Trinity Biotech plc IDA Business Park Bray Co. Wicklow L2 A98 H5C8 Items 5(a)-(b) of the Schedule 13D is amended and supplemented as follows: The information set forth in rows 11 and 13 of the cover pages to this Amendment No. 4 to the Schedule 13D is incorporated by reference. The percentage set forth in row 13 is based on 383,881,600 Ordinary Shares outstanding as of March 15, 2025, as reported in the Issuer's registration statement on Form F-3 filed with the Securities and Exchange Commission on March 21, 2025, and, with respect to Credit Fund II, assumes the exercise of 500,000 Warrants held by Credit Fund II into 500,000 ADSs representing 10,000,000 Ordinary Shares, and with respect to Credit Fund III, assumes the exercise of 2,000,000 Warrants held by Credit Fund III into 2,000,000 ADSs representing 40,000,000 Ordinary Shares. The Warrants may not be exercised if the Reporting Persons would beneficially own more than 9.99% of the Issuer's outstanding Ordinary Shares after giving effect to such exercise. The information set forth in rows 7 through 10 of the cover pages to this Amendment No. 4 to the Schedule 13D is incorporated by reference. Perceptive Advisors LLC /s/ Joseph Edelman 03/25/2025 Perceptive Credit Advisors LLC /s/ Joseph Edelman 03/25/2025 Joseph Edelman /s/ Joseph Edelman 03/25/2025 Perceptive Credit Holdings II, L.P. /s/ Joseph Edelman 03/25/2025 Perceptive Credit Holdings III, L.P. /s/ Joseph Edelman 03/25/2025