X0206 3 2020-10-20 1 0001805387 ARYA Sciences Acquisition Corp II ARYB 0001224962 PERCEPTIVE ADVISORS LLC 51 ASTOR PLACE, 10TH FLOOR NEW YORK NY 10003 1 0 0 0 0001249675 PERCEPTIVE LIFE SCIENCES MASTER FUND LTD C/O PERCEPTIVE ADVISORS LLC 51 ASTOR PLACE, 10TH FLOOR NEW YORK NY 10003 1 0 0 0 1. Perceptive Advisors LLC (the "Advisor") serves as the investment manager of the Perceptive Life Sciences Master Fund Ltd. (the "Master Fund"). Joseph Edelman, the managing member of the Advisor, serves as a director of the Issuer and has filed a separate Form 3. /s/ Perceptive Life Sciences Master Fund Ltd., By: Perceptive Advisors LLC, its investment manager By: Joseph Edelman, its managing member 2020-10-22 /s/ Perceptive Advisors LLC, By: Joseph Edelman, its managing member 2020-10-22