X0306 4 2020-02-10 0 0001261249 AGILE THERAPEUTICS INC AGRX 0001224962 PERCEPTIVE ADVISORS LLC 51 ASTOR PLACE, 10TH FLOOR NEW YORK NY 10003 0 0 1 0 0001249675 PERCEPTIVE LIFE SCIENCES MASTER FUND LTD C/O PERCEPTIVE ADVISORS LLC 51 ASTOR PLACE, 10TH FLOOR NEW YORK NY 10003 0 0 1 0 0001164426 EDELMAN JOSEPH C/O PERCEPTIVE ADVISORS LLC 51 ASTOR PLACE, 10TH FLOOR NEW YORK NY 10003 0 0 1 0 Common Stock 2020-02-25 4 P 0 3000000 3.00 A 14919925 I See footnote Warrants (right to buy) 3.74 2020-02-10 4 J 0 700000 A 2020-02-10 2027-02-10 Common Stock 700000 700000 I See footnote Warrants (right to buy) 4.67 2020-02-10 4 J 0 700000 A 2020-02-10 2027-02-10 Common Stock 700000 700000 I See footnote The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the "Master Fund"). Perceptive Advisors LLC (the "Advisor") serves as the investment manager of Master Fund. Joseph Edelman is the managing member of the Advisor. The securities were acquired by Perceptive Credit Holdings III, L.P. (the "Credit Fund") in connection with a senior secured term loan credit facility entered into with the Issuer. The securities are directly held by the Credit Fund. The Advisor serves as the investment manager of the Credit Fund. Mr. Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of the securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes. /s/ Perceptive Life Sciences Master Fund Ltd., By: Perceptive Advisors LLC, its investment manager By: Joseph Edelman, its managing member 2020-02-25 /s/ Perceptive Advisors LLC, By: Joseph Edelman, its managing member 2020-02-25 /s/ Joseph Edelman 2020-02-25