Stockholders' Equity and Convertible Preferred Stock (Details) - Schedule of option activity - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Schedule of option activity [Abstract]
Outstanding beginning balance, Number of Shares	384,304	88,950
Outstanding beginning balance, Weighted Average Exercise Price	$ 40.15	$ 172.39
Outstanding beginning balance, Total Intrinsic Value	$ 69,000
Outstanding beginning balance, Weighted Average Remaining Contractual Life (in years)		5 years 8 months 12 days
Outstanding ending balance, Number of Shares	479,654	384,304
Outstanding ending balance, Weighted Average Exercise Price	$ 32.35	$ 40.15
Outstanding ending balance, Intrinsic Value		$ 69,000
Outstanding ending balance, Weighted Average Remaining Contractual Life	8 years 2 months 12 days	8 years 10 months 24 days
Options vested and exercisable, Number of Shares	479,654
Options vested and exercisable, Weighted Average Exercise Price	$ 32.35
Options vested and exercisable, Weighted Average Remaining Contractual Life	8 years 2 months 12 days
Employee options granted, Number of Shares	100,000	300,000
Employee options granted, Weighted Average Exercise Price	$ 1.24	$ 0.64
Employee options granted, Total Intrinsic Value		$ 69,000
Employee options granted, Weighted Average Remaining Contractual Life (in years)	9 years 1 month 6 days	10 years
Employee options expired, Number of Shares	(4,650)	(4,646)
Employee options expired, Weighted Average Exercise Price
Employee options expired, Total Intrinsic Value