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Stockholders' Equity and Convertible Preferred Stock (Details 3)
12 Months Ended
Dec. 31, 2019
USD ($)
$ / shares
shares
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number of Shares [Roll Forward]  
Outstanding at beginning | shares 124,381
Employee options expired | shares (35,121)
Non-employee options expired | shares (310)
Outstanding at ending | shares 88,950
Options vested and exercisable | shares 88,950
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Roll Forward]  
Outstanding at beginning | $ / shares $ 209.22
Employee options expired | $ / shares 302.29
Non-employee options expired | $ / shares 571.71
Outstanding at ending | $ / shares 172.39
Options vested and exercisable | $ / shares $ 172.39
Share-based Compensation Arrangement by Share-based Payment Award, Options, Total Intrinsic Value [Roll Forward]  
Outstanding at beginning | $
Employee options expired | $
Non-employee options expired | $
Outstanding at ending | $
Options vested and exercisable | $
Share-based Compensation Arrangement by Share-based Payment Award, Options, Weighted Average Remaining Contractual Life [Roll Forward]  
Outstanding at beginning 4 years 9 months 18 days
Outstanding at ending 5 years 8 months 12 days
Options vested and exercisable 5 years 8 months 12 days