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Subsequent Events (Details) (USD $)
0 Months Ended 1 Months Ended 9 Months Ended 12 Months Ended 1 Months Ended 0 Months Ended 1 Months Ended 3 Months Ended 0 Months Ended 0 Months Ended 1 Months Ended 1 Months Ended 0 Months Ended
Jan. 19, 2011
Oct. 07, 2010
Mar. 31, 2012
Feb. 29, 2012
Oct. 31, 2011
Sep. 30, 2012
Sep. 30, 2011
Dec. 31, 2011
Oct. 08, 2012
Dec. 31, 2010
Oct. 08, 2012
Minimum
Oct. 31, 2011
Rodman & Renshaw, LLC
Jan. 31, 2011
Rodman & Renshaw, LLC
Oct. 31, 2010
Rodman & Renshaw, LLC
Oct. 07, 2010
Rodman & Renshaw, LLC
Sep. 21, 2012
Subsequent event
Apr. 02, 2012
Subsequent event
Nov. 30, 2012
Subsequent event
item
Mar. 31, 2012
Subsequent event
Dec. 31, 2012
Subsequent event
Nov. 07, 2012
Subsequent event
Oct. 08, 2012
Subsequent event
Aug. 14, 2012
Subsequent event
item
Dec. 31, 2011
Subsequent event
Dec. 31, 2010
Subsequent event
Dec. 03, 2012
Subsequent event
Maximum
Nov. 30, 2012
Subsequent event
Maximum
Oct. 08, 2012
Subsequent event
Minimum
Nov. 30, 2012
Subsequent event
Dr. Claire L. Kruger
Nov. 30, 2012
Subsequent event
Mr. Clayton
Nov. 30, 2012
Subsequent event
Other departing employees
Nov. 30, 2012
Subsequent event
Dr. Lodder
Nov. 30, 2012
Subsequent event
2012 Equity Incentive Plan
Feb. 29, 2012
Subsequent event
Securities purchase agreement
Rodman & Renshaw, LLC
Feb. 29, 2012
Subsequent event
Securities purchase agreement
Rodman & Renshaw, LLC
Maximum
Feb. 29, 2012
Subsequent event
Forecast
Feb. 02, 2012
Subsequent event
Forecast
Securities purchase agreement
Feb. 02, 2012
Subsequent event
Forecast
Securities purchase agreement
Maximum
Subsequent Events                                                                            
Number of shares of common stock issued 21,345       26,628                         483,657                                     53,241  
Number of shares of common stock under warrants issued 10,673 10,500     26,628             799 640 630       483,657                                 1,597     10,648
Gross proceeds from issuance of common stock and warrants $ 2,770,000       $ 1,250,000                                                               $ 1,150,000  
Number of common shares under each unit sold 1       1                                                               1  
Number of common shares under each warrant 0.5       1                                                               0.2  
Purchase price per unit (in dollars per share) $ 130.00       $ 47.40                         $ 6.53                                     $ 21.60  
Period after issuance date after which warrants are exercisable                                                                   6 months     6 months  
Warrants exercise price (in dollars per share) $ 160.00 $ 300.00     $ 44.80             $ 59.00 $ 163   $ 312.60           $ 6.53                         $ 27.00     $ 28.00  
Net proceeds from issuance of common stock 2,600,000       1,100,000 1,055,353 2,545,349 3,700,552                                                       1,100,000 1,100,000  
Estimated fair value of warrants at the date of grant                       25,000 42,000 49,000                                       19,000        
Term of Lease     5 years                               5 years                                      
Base annual rent                                 152,500                                          
Percentage of annual increase in base annual rent           3.00%                     3.00%                                          
Number of private offerings of securities                                             1                              
Reverse stock split, exchange ratio                               20                                            
Common stock, par value (in dollars per share)           $ 0.0001   $ 0.0001 $ 0.01 $ 0.0001           $ 0.01   $ 0.0001       $ 0.01                                
Common stock, outstanding shares prior to reverse stock split               3,094,961   2,135,588                                                        
Common stock, outstanding shares after reverse stock split           208,207   155,150   107,182                           154,749 106,781                          
Net proceeds in a private placement of common stock and warrants       1,100,000                           2,300,000                                        
Common stock, sale price per share                                   $ 5.324                                        
Warrants exercisable period (in years)                                   5 years                                        
Investors participation right in future debt or equity offerings of entity (as a percent)                                   100.00%                                        
Period after closing of private placement for investor's participation right in future debt or equity offerings of entity (in years)                                   2 years                                        
Common stock, traded price (in dollars per share)                     $ 1.00                                 $ 1.00                    
Number of consecutive business days for which entity's share price traded above $1.00 per share                                                       10 days                    
The number of Board of Directors members                                   8                                        
Percentage of common stockholders authorized to approve specific actions                                   70.00%                                        
Common stock, shares authorized           50,000,000   50,000,000   50,000,000               50,000,000                                        
Preferred stock, shares authorized           5,000,000   5,000,000   5,000,000               5,000,000                                        
Preferred stock, par value (in dollars per share)           $ 0.01   $ 0.01   $ 0.01               $ 0.0001                                        
Shares of common stock that may be issued                                                                 125,000          
Number of shares of common stock issuable upon exercise of Series B Warrants issued in a private placement B Warrants                                         483,657           483,657                      
Nominal consideration                                                   1,000                        
Loss on sale of subsidiary                                       1,300,000                                    
Bonus paid                                                         143,000                  
Severance                                                         286,000                  
Severance costs payable                                                           212,180 211,000              
Bonus payable                                                           $ 74,263 $ 82,000 $ 93,359