X0306 4 2018-03-15 0 0001299130 PACIFIC BIOSCIENCES OF CALIFORNIA, INC. PACB 0001222643 ORDONEZ KATHY PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 1305 O'BRIEN DRIVE MENLO PARK CA 94025 1 1 0 0 Chief Commercial Officer Common Stock 2018-03-15 4 A 0 43750 0.00 A 43750 D Stock Option (right to buy) 2.63 2018-03-15 4 A 0 87500 0.00 A 2018-03-15 2028-03-15 Common Stock 87500 87500 D Each share is represented by a Restricted Stock Unit ("RSU"). The RSUs will vest in equal annual installments on February 15 of each of 2019, 2020, 2021, and 2022, provided that the Reporting Person continues to serve through each vesting date. The shares subject to the option will vest in equal monthly installments over the next four years, provided that the Reporting Person continues to serve through each vesting date. /s/ Stephen Moore, Attorney-in-fact for Kathy Ordonez 2018-03-16