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      <issuerContactPhone>617-714-6500</issuerContactPhone>
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      <relationshipsToIssuer>
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          <com:street2>6th Floor</com:street2>
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        <name>Flagship Ventures Fund IV-Rx  LP</name>
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          <com:stateOrCountry>MA</com:stateOrCountry>
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        <name>Flagship Ventures Fund IV-Rx  LP</name>
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        <name>Flagship Ventures Fund IV-Rx  LP</name>
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          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02139</com:zipCode>
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      <securitiesClassTitle>Common</securitiesClassTitle>
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        <name>Flagship Ventures Fund IV-Rx  LP</name>
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        <name>Flagship Ventures Fund IV-Rx  LP</name>
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          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02139</com:zipCode>
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        <name>Flagship Ventures Fund IV-Rx  LP</name>
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          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02139</com:zipCode>
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    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Flagship Ventures Fund IV-Rx  LP</name>
        <address>
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          <com:stateOrCountry>MA</com:stateOrCountry>
          <com:zipCode>02139</com:zipCode>
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      </sellerDetails>
      <securitiesClassTitle>Common</securitiesClassTitle>
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    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Flagship Ventures Fund IV-Rx  LP</name>
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    <remarks>Sales are being executed by Flagship Ventures Fund IV-Rx, L.P.</remarks>
    <noticeSignature>
      <noticeDate>06/11/2024</noticeDate>
      <signature>/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for  Flagship Ventures Fund IV-Rx, L.P.</signature>
    </noticeSignature>
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