X0306 4 2018-05-14 0 0001048477 BIOMARIN PHARMACEUTICAL INC BMRN 0001221590 BIENAIME JEAN JACQUES C/O BIOMARIN PHARMACEUTICAL INC. 770 LINDARO ST. SAN RAFAEL CA 94901 1 1 0 0 Chief Executive Officer Common Stock 2018-05-14 2018-05-14 4 M 0 18750 38.590 A 309350 D Common Stock 2018-05-14 2018-05-14 4 S 0 18750 89.2187 D 290600 D Common Stock 2018-05-15 2018-05-15 4 M 0 18750 38.590 A 309350 D Common Stock 2018-05-15 2018-05-15 4 S 0 18750 88.2898 D 290600 D Common Stock 182201 I Shares held by Jean-Jacques Bienaime Family Trust Stock Option (Right to buy Common Stock) 38.59 2018-05-14 2018-05-14 4 M 0 18750 0 D 2008-11-22 2018-05-21 Common Stock 18750 56250 D Stock Option (Right to buy Common Stock) 38.59 2018-05-15 2018-05-15 4 M 0 18750 0 D 2008-11-22 2018-05-21 Common Stock 18750 37500 D Trade made pursuant to a 10b5-1 plan executed on November 14, 2017. The price in column 4 is the weighted average price. The price actually received ranged from $88.406 to $89.84. The reporting person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price. The price in column 4 is the weighted average price. The price actually received ranged from $87.65 to $88.70. The reporting person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price. Reflects the number of options outstanding after the transactions from this specific stock option grant. /s/ Laura Randall Woodhead, Attorney-in-Fact 2018-05-16