X0306 4 2015-04-01 0 0001048477 BIOMARIN PHARMACEUTICAL INC BMRN 0001221590 BIENAIME JEAN JACQUES C/O BIOMARIN PHARMACEUTICAL INC. 770 LINDARO ST. SAN RAFAEL CA 94901 1 1 0 0 Chief Executive Officer Common Stock 2015-04-01 2015-04-01 4 M 0 22546 6.46 A 55804 I Shares held by Bienaime Family Trust Common Stock 2015-04-01 2015-04-01 4 S 0 22546 120.5334 D 33258 I Shares held by Bienaime Family Trust Common Stock 2015-04-01 2015-04-01 4 S 0 3506 120.5334 D 251251 D Stock Option (right to buy) Common Stock 6.46 2015-04-01 2015-04-01 4 M 0 22546 0 D 2005-11-11 2015-05-10 Common Stock 22546 23218 I Shares held by Bienaime Family Trust Trade made pursuant to a 10b5-1 plan executed October 28, 2014. The reporting person an his spouse act as trustees for the Bienaime Family Trust The price in column 4 is an average weighted price. The price actually received ranged from $118.4 to $124.61. The issuing person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the amount of shares sold at each price within the range. Original option grant vests 6/48th on November 11, 2005, and 1/48th on the 11th day of every month thereafter. Reflects the numbers of stock options outstanding after the transaction from this specific stock option grant. /s/ Laura Randall Woodhead, Attorney-in-Fact 2015-04-03