X0306 4 2021-08-09 0000012208 BIO-RAD LABORATORIES, INC. BIO BIOB 0001629381 Crowley Michael C/O BIO-RAD LABORATORIES, INC. 1000 ALFRED NOBEL DRIVE HERCULES CA 94547 0 1 0 0 EVP, GBL Commercial Operations Bio-Rad A Common Stock 2021-08-09 4 M 0 3000 139.56 A 6669 D Bio-Rad A Common Stock 2021-08-09 4 S 0 2570 754.80 D 4099 D Bio-Rad A Common Stock 2021-08-09 4 S 0 430 755.72 D 3669 D Non-Qualified Stock Option (right to buy) 139.56 2021-08-09 4 M 0 3000 0 D 2025-09-11 Bio-Rad A Common Stock 3000 0 D The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $754.52 to $755.39, inclusive. The reporting person undertakes to provide to Bio-Rad Laboratories, Inc., any security holder of Bio-Rad Laboratories, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $755.52 to $756.30, inclusive. The reporting person undertakes to provide to Bio-Rad Laboratories, Inc., any security holder of Bio-Rad Laboratories, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The option, representing a right to purchase a total of 3,000 shares, became exercisable in five equal annual installments beginning on September 11, 2016, which was the first anniversary of the date on which the option was granted. /s/ Michael Crowley 2021-08-09