X0303 4 2011-01-14 0 0000859737 HOLOGIC INC HOLX 0001218713 CASCELLA ROBERT 35 CROSBY DRIVE BEDFORD MA 01730 1 1 0 0 CEO and President Common Stock 2011-01-14 4 F 0 12709 19.17 D 286350 D Common Stock 2011-01-14 4 F 0 12525 19.17 D 273825 D The disposition of 12,709 shares of common stock reported on this Form 4 relates to a tax withholding transaction in connection with the vesting of restricted stock units. The disposition of 12,525 shares of common stock reported on this Form 4 relates to a tax withholding transaction in connection with the vesting of restricted stock units. By: Mark J. Casey, Attorney-In-Fact For: Robert A. Cascella 2011-01-17