<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2005-03-15</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000784199</issuerCik>
        <issuerName>CRYOLIFE INC</issuerName>
        <issuerTradingSymbol>CRY</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001218321</rptOwnerCik>
            <rptOwnerName>OSS CAPITAL MANAGEMENT</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>598 MADISON AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2000000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnotes</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>6% Convertible Preferred Stock (the &quot;Preferred Stock&quot;)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>8.04</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F4"/>
            </exerciseDate>
            <expirationDate>
                <value>2015-04-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>528607</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnotes</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">O.S.S. Capital Management LP, a Delaware limited partnership (the &quot;Investment Manager&quot;), serves as (i) investment manager to
a Cayman Islands exempted company and (ii) management company to two Delaware limited partnerships (collectively with the
Cayman Islands exempted company, the &quot;Funds&quot;) and has investment discretion with respect to securities held by the Funds.
Schafer Brothers LLC, a Delaware limited liability company (the &quot;SB LLC&quot;), serves as the general partner to the Investment
Manager, and has investment discretion with respect to securities held by the Funds. Mr. Oscar S. Schafer (&quot;Mr. Schafer&quot;)
serves as the senior managing member of SB LLC and has investment discretion with respect to securities held by the Funds.</footnote>
        <footnote id="F2">Each of the Investment Manager, SB LLC and Mr. Schafer may be deemed to beneficially own 2,000,000 shares of common stock and
85,000 shares of Preferred Stock convertible into 528,607 shares of common stock, which represent, together, approximately
10.4% of the outstanding shares of common stock.</footnote>
        <footnote id="F3">Each of the Investment Manager, SB LLC, and Mr. Schafer disclaims beneficial ownership of the securities included in this
report and this report shall not be deemed an admission that either the Investment Manager, SB LLC, or Mr. Schafer is the
beneficial owner of such securities for purposes of Section 16 or for any other purpose.</footnote>
        <footnote id="F4">Preferred Stock is immediately exercisable.</footnote>
    </footnotes>

    <remarks>Exhibit List:

Exhibit 99 - Joint filer information</remarks>

    <ownerSignature>
        <signatureName>/s/ Oscar S. Schafer</signatureName>
        <signatureDate>2005-08-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
