X0306 4 2018-06-29 0 0001217234 CareDx, Inc. CDNA 0001613855 Maag Peter C/O CAREDX, INC. 3260 BAYSHORE BOULEVARD BRISBANE CA 94005 1 1 0 0 See Remarks Common Stock 2018-06-29 4 A 0 150000 0.00 A 422037 D Common Stock 2018-06-29 4 A 0 50000 0.00 A 472037 D Common Stock 1000 I As UTMA custodian for minor child Common Stock 1000 I As UTMA custodian for minor child Employee Stock Option (right to buy) 12.24 2018-06-29 4 A 0 150000 0.00 A 2028-06-29 Common Stock 150000 150000 D The reported securities are represented by restricted stock units, 1/4th of which shall vest on June 1, 2019 and 1/4th of which shall vest on each anniversary thereafter. The reported securities are represented by restricted stock units, 100% of which were vested upon grant. Shares are held of record by the Reporting Person as custodian for a minor child under the Uniform Transfer to Minors Act. The Reporting Person disclaims beneficial ownership of these shares, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose. 1/4th of the shares subject to the option shall vest on June 1, 2019 and 1/48th of the shares subject to the option shall vest monthly thereafter. President and Chief Executive Officer /s/ Peter Maag 2018-07-03