X0306 4 2018-03-20 0 0001217234 CareDx, Inc. CDNA 0001613855 Maag Peter C/O CAREDX, INC. 3260 BAYSHORE BOULEVARD BRISBANE CA 94005 1 1 0 0 See Remarks Common Stock 2018-03-20 4 M 0 50000 0.548 A 287037 D Common Stock 1000 I As UTMA custodian for minor child Common Stock 1000 I As UTMA custodian for minor child Stock Option (Right to Buy) 0.548 2018-03-20 4 M 0 50000 0.00 D 2012-11-01 2022-10-17 Common Stock 50000 50000 D Shares are held of record by the Reporting Person as custodian for a minor child under the Uniform Transfer to Minors Act. The Reporting Person disclaims beneficial ownership of these shares, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose. 2/48ths of the shares subject to this option vested and became exercisable on the Date Exercisable set forth in column 6 and each month thereafter until October 1, 2013. 1/36th of the remaining shares vested and became exercisable each month thereafter. President and Chief Executive Officer /s/ Peter Maag 2018-03-21