X0306 4 2016-09-26 0 0001217234 CareDx, Inc. CDNA 0001613855 Maag Peter C/O CAREDX, INC. 3260 BAYSHORE BOULEVARD BRISBANE CA 94005 1 1 0 0 President and CEO Common Stock 2016-09-26 4 P 0 10000 4.00 A 87250 D Common Stock 1000 I As UTMA custodian for minor child Common Stock 1000 I As UTMA custodian for minor child Includes 3,000 shares that Reporting Person acquired pursuant to Issuer's 2014 Employee Stock Purchase Plan on July 1, 2016. Shares are held of record by the Reporting Person as custodian for a minor child under the Uniform Transfer to Minors Act. The Reporting Person disclaims beneficial ownership of these shares, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose. Shares are held of record by the Reporting Person as custodian for a minor child under the Uniform Transfer to Minors Act. The Reporting Person disclaims beneficial ownership of these shares, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of these securities for purposes of Section 16 or for any other purpose. /s/ Charles Constanti, by power of attorney 2016-10-04